Rhabdomyolysis in children with chronic renal Failure

Serum myoglobin, as an indicator of rhabdomyolosis, was measured by turbidimetry in the sera of 13 children and adolescents with end stage renal disease [ESRD] before and after the hemodialysis session as well as 9 children and adolescents with moderate chronic renal failure on conservative management [CRF]. Their data were compared to those of 26 age and serum matched healthy subjects aiming to uncover the contribution of rhabdomyolysis to exercise intolerance and possibly to further deterioration in rental functions in uremic children. The serum myoglobin levels were below the detection level of the turbitime system [< 50 mug/L] in the healthy well built control subjects. On the other h and, 78% of children with CRF and 69% of those with ESRD had values >50 mug/L and the differences from the control levels were statistically highly significant [P <0.001]. The two uremic patient groups were quite comparable as far as their serum myoglobin concentrations were concerned [P >0.05]. Body weights and heights did not influence the serum myoglobin levels in the uremic children neither did the gender or the presence of urinary tract infections

Detection of rubella antibodies in infants with congenital anomalies

In this work estimation of IgG and IgM rubella antbodies was done for 153 infants with congenital anomalies and 75 apparently healthy controls in order to diagnose congenital rubella infection. The method applied was hemagglutination inhibition [HAI] microtiration test using procedure of serum treatment with O.23. 2-mercaptoethanol [0.2M. 2ME]. Rubella antibodies were found in 91.5% of patients and 82.6% of controls while I[g]M rubella antibodies were present in 11.1% of patients and could not be detected in controls. This indicated that congenital rubella infection still accounts for a considetrable proportion of congenital abnormalities in Egypt. Therefore, it is important to vaccinate susceptible females before marriage or pregnancy

Campylobacter enteritis in children

Two hundred fecal samples were collected from different infants and children up to the age of 10 years. They included 150 patients suffering from acute diarrhea while the remaining 50 were acting as control. Campylobacter organisms were isolated from the control group. This may indicate the evident pathogenicity of campylobacter as a cause of infective gastroenteriti