Optic nerve metastasis from squamous cell carcinoma of the uterine cervix

Metastatic involvement of the optic nerve or its sheath is very rare [1.3 - 3%]. The most common malignancies reported to metastasize to the optic nerve or its sheath are breast, lung, kidney, bladder, gastric and colorectal cancers. Carcinoma of uterine cervix metastatic to optic nerve and optic nerve sheath is extremely rare and is associated with grave prognosis due to underlying high tumor burden. Here in, we report a 61-year Saudi woman who was treated with concurrent chemoradiation for squamous cell carcinoma of cervix FIGO IVA 6 months back. She presented with pain and progressive visual loss in the right eye. Magnetic resonance imaging showed enhanced solid mass of the intraorbital optic nerve consistent with optic nerve sheath meningioma. Immunostaining [CK5/6, CAM 5.2, p63 and p16] confirmed the diagnosis of metastatic squamous cell carcinoma of uterine cervix

Primary thyroglossal duct cyst papillary carcinoma: a case report

A Thyroglossal duct cyst [TGDC] is the most frequent congenital cervical anomaly [70% in children and 7% in adults] in the development of the thyroid gland. However, incidence of carcinoma arising from a TGDC is extremely rare [

Renal cell carcinoma metastasizing to parotid gland

Renal cell carcinoma [RCC] has diverse behaviour. At the time of diagnosis, many patients are found to have metastases. Bones, lungs, liver and brain are the frequent homing sites of metastases. Parotid gland metastasis is the rarest manifestation of RCC. Here-in we report a case of a 70 year old Saudi male who underwent radical left nephrectomy in February 1997 for renal cell carcinoma [RCC] pT2N0M0. After remaining asymptomatic for 15 years, in January 2012, he presented with four months history of left cheek mass. Subsequent computed tomography [CT] and CT- positron emission tomography [PET] imaging showed left parotid lesion of size 1.3 cm. Patient underwent left parotidectomy. Histopathology was consistent with metastatic RCC. At nine months after metastatectomy, patient was doing well without any disease recurrence

Adenocarcinoma of oesophagus metastasising to the subcutaneous soft tissue

Skin and subcutaneous metastases are uncommon, and mostly originating from cancers of the breast, kidney, colon, lung, and melanoma. Oesophageal cancers rarely metastasise to the skin and subcutaneous soft tissue. Skin and subcutaneous metastases are associated with dismal prognosis. Only few related case reports have been published so far. In this report, we describe a 52 year old patient with lower oesophageal adenocarcinoma who developed subcutaneous metastasis, 9 months after neoadjuvant che-moradiation followed by trans-hiatal esophagectomy