RESUMO
Immunoproliferative small intestinal disease (IPSID) is a poorly recognized cause of malabsorption syndrome in India. Clinicopathological features of five patients with IPSID seen over a two-year period are described. Our data suggest that IPSID is commonly misdiagnosed as intestinal tuberculosis due to lack of awareness and reluctance to obtain small bowel biopsies. Empirical institution of anti-tubercular chemotherapy not only leads to delayed diagnosis but also possibly alters the natural history of the disease, resulting in an intermediate phase of amelioration followed by a terminal phase of lymphomatous transformation. The disease is therefore usually diagnosed at an advanced stage and hence is associated with a relatively poor outcome.
Assuntos
Adulto , Diagnóstico Diferencial , Feminino , Humanos , Doença Imunoproliferativa do Intestino Delgado/diagnóstico , Enteropatias/diagnóstico , Masculino , Pessoa de Meia-Idade , Tuberculose Gastrointestinal/diagnósticoRESUMO
Features of acquired zinc deficiency syndrome occurred in an alcoholic cirrhotic during hospital stay while he was on parenteral nutrition. Rapid reversal of symptoms occurred with resumption of normal diet without additional zinc supplementation.
Assuntos
Adulto , Deficiências Nutricionais/dietoterapia , Humanos , Cirrose Hepática Alcoólica/complicações , Masculino , Parapsoríase/etiologia , Indução de Remissão , Zinco/deficiênciaRESUMO
Pathological spectrum as seen in sixteen cases of gliosarcomas out of 81 cases of glioblastomas is described. Temporal lobe involvement (37.5%) and fibrosarcomatous pattern (62.5%) were found to be most frequent. Osteochondromatous element was found in recurrence of one gliosarcoma. Minimal criteria for diagnosis, pitfalls in diagnosis, differential diagnosis and histogenesis of gliosarcoma are discussed.
Assuntos
Adolescente , Adulto , Neoplasias Encefálicas/patologia , Feminino , Gliossarcoma/patologia , Humanos , MasculinoAssuntos
Adolescente , Encefalopatias/complicações , Quimioterapia Combinada , Evolução Fatal , Encefalopatia Hepática/induzido quimicamente , Humanos , Icterícia/complicações , Fígado/patologia , Masculino , Manitol/uso terapêutico , Necrose , Neomicina/uso terapêutico , Fenobarbital/uso terapêutico , Ácido Valproico/efeitos adversosRESUMO
OBJECTIVE: Histological and mucin secretion patterns were studied in 32 cases of solitary rectal ulcer syndrome. METHODS: Biopsy sections stained with hematoxylin and eosin, Masson's trichrome and alcian blue with PAS at pH 1.0 and pH 2.5 were examined. RESULTS: Fibrosis and smooth muscle extension in lamina propria and hypertrophy of muscularis mucosa were the most frequent histological findings. Sialomucin was present in all cases, in contrast to sulphomucin which is normally present. CONCLUSION: Mucin staining pattern appears to be a helpful diagnostic marker of solitary rectal ulcer syndrome and may be helpful in differentiating it from other non-malignant conditions.
Assuntos
Humanos , Mucosa Intestinal/metabolismo , Mucinas/análise , Doenças Retais/patologia , Sialomucinas , Coloração e Rotulagem , Úlcera/patologiaRESUMO
A case of disseminated carcinoma stomach at the age of thirteen years is reported. The patient in addition had spontaneous bacterial peritonitis.
Assuntos
Infecções por Acinetobacter , Adenocarcinoma Mucinoso/complicações , Adolescente , Idade de Início , Humanos , Hospedeiro Imunocomprometido , Masculino , Peritonite/microbiologia , Neoplasias Gástricas/complicaçõesRESUMO
Campylobacter jejuni is an infrequent cause of self limiting acute diarrheal disease in adults in the Indian subcontinent. We report the occurrence of a life threatening diarrhea due to C jejuni infection in a patient with immunoproliferative small intestinal disease. We postulate that immunosuppression due to malignancy, malnutrition and cancer chemotherapy was responsible for the unusually severe diarrhea.