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Background: Stroke is the second most common cause of mortality worldwide and a major contributor to morbidity and chronic adult disability. To study the prognostic significance of serum cortisol and serum albumin in patients of ischemic stroke was the objective.Methods: This hospital based observational cohort prospective study was undertaken in the Department of Medicine in collaboration with the Departments of Radio diagnosis and Pathology, Jawahar Lal Nehru Medical College and Hospital, AMU, Aligarh from January 2017 to November 2018. By convenience method for sampling, 102 patients who were admitted with the diagnosis of acute ischemic stroke to IPD of JNMCH, Aligarh, on clinical as well as radiological grounds were taken into study.Results: Mean cortisol was 450.84±190.35 nmol/L. The (mean±SD) of serum cortisol was 258.10±77.91 ng/ml in patients with good outcome and 585.77±113.34ng/ml in patients with poor outcome. (p<0.05, r= 0.812). Mean serum albumin was 2.83±0.76 gm/dl. The (mean±SD) of serum albumin was 3.47±0.64mg/dl in patients with good outcome and it was comparatively lower in patients with poor outcome (2.38±0.45mg/dl). (p <0.01, r=-0.659).Conclusions: Serum albumin, serum cortisol are prognostic indicators of functional outcome at 3 months in patients of ischemic stroke.
RESUMO
Background: Neonatal survival is influenced much by care provided by the family before, during and after delivery, which in turn is influenced by mother’s beliefs, and perceptions of her immediate family. Objective: To assess the behaviour of pregnant women regarding good and harmful neonatal care practices. 2. Implementation and assessing impact of Behaviour Change Communication (BCC) Package among pregnant women regarding good and harmful neonatal care practices. Methods: A community based intervention study was conducted in the field practice area of the Urban Health Training Centre, Department of Community Medicine, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh, Uttar Pradesh, India. 200 pregnant women were enrolled purposively. Data were analyzed with Epi Info version 3.5.1. Percentages, and Chi Square Test used. Results: Due to implementation of BCC Package in intervention, good practices like giving colostrum were increased two times. Initiation of breastfeeding within 1 hour was increased 4.7 times, exclusive breastfeeding was gone up 3.8 times and induction of burping was increased 6 times. There was significant difference (P–value <0.05) between the two groups on 7th and 28th days of delivery. Harmful practices like not washing hand were decreased 3.83 times, use of dark and ill-ventilated room was decreased 2.54 times, and practice of cutting the cord with a used blade, or any unsterile scissors, knife, or sickle, broken cup was decreased 3 folds. Application of ghee/ cow dung on the cord was decrease significantly. Practices of prelacteals and use of pacifier, application of kajal, and witch craft for neonatal illnesses were reduced significantly. Conclusion: There was significant improvement in pregnant women regarding traditional neonatal practices. Some practices had not changed due to some strong cultural beliefs and influence of mother in-law and elderly females of the family.