Disproportionate rise in serum CA 125 in case of budd chiari syndrome: an unusual presentation.

Ca 125 is used as a diagnostic and prognostic biomarker for ovarian cancer. The level of CA 125 is also elevated in benign conditions like Budd Chiari syndrome, liver cirrhosis and heart failure. But very high level of CA 125 is rarely associated with benign conditions and this can mislead the physician. Here we present a case of budd chiari syndrome in postpartum period associated with very high level of CA 125 which is an unusual presentation.

Ascites in CML: a rare extramedullary manifestation.

Ascites in chronic myeloid leukemia (CML) as an extramedullary manifestation is rarely reported in the literature. A young 23 year old female of chronic myeloid leukemia presenting with extramedullary disease as massive ascites. All stages of granulocytes and a few blasts similar to peripheral blood smear was present in ascitic fluid. Based on clinical symptoms and signs, bone marrow examination, ascitic fluid cytology and ultrasonography of abdomen she was diagnosed as a case of Chronic myeloid leukemia in chronic phase with extramedullary disease as massive ascites. After starting treatment with Imatinib mesylate favourable response was observed.

Abamectin: an uncommon but potentially fatal cause of pesticide poisoning.

Human intoxication with abamectin is not frequently reported. It is an uncommon but potentially fatal cause of pesticide poisoning. In contrast to common organophosphate poisoning the toxic effects of avermectin in humans are not clearly defined. Ingestion of a large dose of avermectin may be associated with life-threatening complications. The therapy for avermectin poisoning is mainly symptomatic and supportive. The prognosis of patients with avermectin poisoning is likely to be favorable unless they are complicated by severe hypotension or aspiration. We hereby report a case with abamectin poisoning with neurological toxicity and respiratory failure which responded to supportive line of therapy.