Papillary thyroid carcinoma; the frequency of multifocality in patients undergoing total thyroidectomy

At Mayo Hospital Lahore, from August 2010 to April 2011. Was to determine the frequency of multifocality among all cases presented with papillary thyroid carcinoma [PTC] planned to undergo total thyroidectomy [TT]. Data of all patients of PTC was collected from inpatient department of East Surgical ward. All the patients underwent total thyroidectomy by same team of consultant surgeons. A total of 35 patients of PTC with mean age of 37.94 years were included. Multifocal tumor was found in 31.4%. Out of them, 72.7% were females and 27.3% males. This case series showed that a multifocality is highly prevalent in PTC and total thyroidectomy should be done as the treatment for PTC, to eliminate the additional tumor foci in thyroid gland and prevent its recurrence

Parathyroid carcinoma

Parathyroid carcinoma is a rare endocrine malignancy accounting for less than 1% of all cases of hyperparathyroidism. We present a case of a middle-aged woman who was undiagnosed for 3 years before presenting with renal stones and advanced musculoskeletal disease. Investigations revealed primary hyperparathyroidism. Focused cervical exploration and left inferior parathyroidectomy was carried out based on the pre-operative localization studies. Parathyroid carcinoma was diagnosed on histopathology postoperatively. Subsequent en bloc resection was not performed and the patient is being monitored with serial parathyroid hormone levels which have not shown any increase in 6 months of follow-up. Only two previous cases of parathyroid carcinoma have been reported from Pakistan