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INTRODUCTION:The present investigation was undertaken to correlation between mortality and morbidity (organ dysfunction [OD]) and score for neonatal acute physiology-II (SNAP-II).MATERIALS AND METHODS:A prospective investigation of newborns neonates, a total 157 neonates 82 male (52.2%), female 75 (47.8%) were enrolled and disunited into four groups according to gestational age: 28 to 30 weeks (G1), 31 to 33 (G2) 34 to 36 weeks (G3) and >37 weeks (G4) variables analyzed were SNAP II.RESULTS AND DISCUSSION:The receiver operating characteristic curve for SNAP-II score and death is more predictive in correlation to OD (area under curve of death is 0.776 as compared to 0.553 for OD). The sensitivity, specificity, positive predictive value, and negative predictive value of SNAP-II score with mortality (outcome) were 42.8%, 100%, 100%, and 82.3%, respectively.CONCLUSION:The SNAP-II revealed efficient to fantabulous ?40 can prognosticate OD and death when applied on admission to neonates with sepsis.
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We have analyzed the suitability and potential of Oral Fluid (OF) to substitute serum in estimating measles IgG antibodies, during community surveys, by comparing the Optical Density (OD) of measles IgG antibodies in OF and serum of 100 apparently asymptomatic children. IgG antibody status was determined using commercially available - Measles IgG Capture ELISA. Sensitivity 89.5%, specificity 90.6% Concordance of 89%, coefficient of correlation r is equal to 0.97 (Karl Pearson's) and rho is equal to 0.86 (Spearman's), was found between OD value of OF and serum. The study emphasizes the potential of OF to surrogate serum in estimating Measles IgG antibody among children. The OF collection is advantageous over blood as it is painless. It is suitable for non-technical staff, easy to transport and less bio-hazardous.