Comparative study of serum lipid concentrations in preeclampsia and normal pregnancy.

OBJECTIVE: To compare serum lipids in mild, severe preeclamptic women and normal pregnant women. STUDY DESIGN: Cross-sectional study. SETTING: Section of Obstetrics and Gynecology, Taksin Hospital. MATERIAL AND METHOD: The data was collected from 65 normal pregnant women, 40 mild preeclamptic women, and 48 severe preeclamptic women. The blood samples were collected and analyzed for cholesterol, triglyceride, high-density lipoprotein (HDL), and low-density lipoprotein (LDL). The data was analyzed using Analysis of Variances (ANOVA). RESULTS: There was no significant difference in serum cholesterol, triglyceride, HDL, and LDL between normal, mild, and severe preeclamptic women. CONCLUSION: There was no correlation between serum lipids in normal pregnancy and preeclampsia.

Serum calcium, magnesium and uric acid in preeclampsia and normal pregnancy.

OBJECTIVE: To compare serum calcium, magnesium and uric acid in mild, severe preeclamptic women and normal pregnant women. STUDY DESIGN: Cross-sectional study. Setting: Section of Obstetrics and Gynecology, Taksin Hospital. MATERIAL AND METHOD: The data was collected from 36 normal pregnant women, 35 mild preeclamptic women and 33 severe preeclamptic women who were admitted in the Section of Obstetrics and Gynecology at Taksin Hospital between April 2006 and June 2007. The blood samples were collected and analyzed for calcium, magnesium and uric acid The data was analyzed using Analysis of Variances (ANOVA). RESULTS: The serum calcium in severe preeclamptic women was significantly lower (8.7 +/- 0.59 mg/dl vs. 8.99 +/- 0.31 mg/dl, p = 0.045; and 9.05 +/- 0.52 mg/dl, p = 0 014) and serum uric acid was significantly higher (7.01 +/- 1.93 mg/dl vs. 5.33 +/- 1.23 mg/dl, p < 0.001 and 5.95 +/- 1.9 mg/dl, p = 0.044) than in normal pregnant women and mild preeclamptic women respectively, but there was no difference between normal and mild preeclamptic women. There was no difference in serum magnesium among normal pregnancy and both groups of preeclampsia. CONCLUSION: Hypocalcemia and hyperuricemia correlated to severe preeclampsia.