Study on the predictive value of island sign and coagulation function in hematoma enlargement of hypertensive intracerebral hemorrhage / 中风与神经疾病杂志

@#Objective　To explore the relationship between island sign,coagulation function and hematoma enlargement of HICH,and to study their predictive value for hematoma enlargement.Methods　We selected HICH patients in the Department of Neurosurgery of Wuhan Puren Hospital from January 2019 to January 2021 as the research objects.According to whether there is an enlarged hematoma,the patients were divided into an enlarged hematoma group and an unexpanded hematoma group.We compared the baseline data of the two groups and used a multivariate logistics regression analysis method to analyze independent risk factors for hematoma enlargement.We used ROC curve and AUC to analyze and compare the predictive value of island sign and coagulation function for hematoma enlargement of HICH.Results　Whether the hematoma breaks into the ventricle,island sign,GCS score,PT,INR,hematoma volume,blood sugar level is related to hematoma enlargement of HICH (P＜0.05).Among them,the island sign,GCS score,PT,and whether the hematoma breaks into the ventricle are independent risk factors for hematoma enlargement of HICH (P＜0.05).The AUC of island and coagulation function＞AUC of individual island sign and AUC of individual coagulation function (P＜0.05).Conclusion　Compared with the island sign or PT alone,the island sign combined with PT has a better predictive value for hematoma enlargement of HICH.

Diagnosis and treatment of ketamine-associated cystitis：A report of 3 cases and literature review / 中南大学学报(医学版)

Objective:To determine the diagnosis, treatment, and pathogenesis of ketamine-associated cystitis. Methods:Clinical data from 3 patients with ketamine-associated cystitis were analyzed retrospectively and discussed in light of relevant literature. Results:In the 3 cases, 2 presented severe lower urinary tract symptoms, including frequency, urgency, dysuria, urge incontinence, and painful haematuria. Urinalysis and urine culture were negative. Imaging examination demonstrated thickening of the bladder wall and a small capacity. Inflammatory changes in the bladder mucosa were observed by cystoscopy and biopsies. After cessation of ketamine use, with the addition of steroids or hydrodistension, the symptoms in the 3 patients improved. The symptoms recurred in 2 patients, as 1 was exposed to ketamine again and 1 had severe bladder contraction after for 3-4 month follow-up. Conclusion:Ketamine-associated cystitis is a new urinary system inlfammatory damage. Its etiology and treatment methods are not clear. early abstinence from ketamine use and early treatment are crucial for patients with ketamine-associated cystitis to avoid irreversible damage.

Chylous leakage after retroperitoneoscopic upper-pole heminephrectomy for duplex kidney / 中南大学学报(医学版)

OBJECTIVE@#To discuss management of chylous leakage after retroperitoneoscopic upper-pole heminephrectomy for duplex kidney.@*METHODS@#Between November 2004 and Februar y 2011, 39 patients underwent retroperitoneoscopic upper-pole heminephrectomy for duplex kidney, of these 5 patients had chylous leakage. The ages of the patients ranged from 32 to 60 years (mean 42). All the patients were treated conservatively, and the therapeutic effects were observed.@*RESULTS@#Delayed chylous leakage in 5 patients occurred 5-31 days after surgery, and leakage occurred in 4 of the same 5 patients during the first 2 post-operative years. Chylous leakage after retroperitoneoscopic upper-pole heminephrectomy for duplex kidney preferentially occurred at the left side of duplex kidney. All the patients healed under conservative treatment.@*CONCLUSION@#Chylous leakage typically occurs after left retroperitoneoscopic upper-pole heminephrectomy for duplex kidney, and can be prevented by improving surgical technique; it can be completely relieved by conservative management with satisfactory results.

A clinical efficacy and safety study on coronary heart disease and angina treatment with Puerarin Injection / 中华流行病学杂志

Objective To observe the clinical efficacy and safety of Puerarin Injection treatment on angina pectoris.Methods 388 patients with angina pectoris,enrolled to Tianjin Fourth Central Hospital during January 2009 and February 2011 were selected and randomly divided into treatment or control groups with 194 patients of each.Based on the conventional therapy program,one group was given Puerarin Injection as treatment group while,the other was given with Danshen Injection as control group.Clinical efficacy,the attack rate of angina pectoris,oxygen consumption,iadices on electrocardiogram,haemorheology and other adverse reactions among the two groups were compared.Results The total efficacy of the treatment group (88.14％,171/194)was significantly higher than the control group (61.86％,120/194) and the difference was statistically significant (P＜0.05).During the treatment,no significant adverse events were noticed in both of the two groups of patients.Conclusion The Puerarin Injection treatment program on angina pectoris seemed effective and safe.

Clinical studies on different coronary artery interventional therapies through femoral artery or radial artery approaches / 中华流行病学杂志

Objective To compare the clinical efficacies regarding femoral artery or radial artery approaches on coronary artery interventional therapies.Methods 360 patients were randomly divided into intervention group via femoral artery (TFI) or transradial coronary intervention (TRI) group.Postoperative observation on the two said groups of patients with vascular lesion characteristics,feasibility factors ( success rate of interventional therapy puncture,time of operation and hospitalization)and complications,were made.Results There were no significant differences between the two groups on the characteristics of vascular lesion (P＞0.05).Success rates of the two groups were 97.78％ and 96.67％ respectively.The differences on success rate,time of operation were not statistically significant (P＞0.05) while the average time of puncture,the mean duration of hospitalization and the rates of complications were significantly different ( P＜ 0.05 ).Conclusion The two methods under comparison had similar success rate and feasibility.However,the complications related to radial artery interventional therapy were much less than the femoral artery interventional therapy.As having better safety,radial artery interventional therapv seemed to have applicable value on clinical oractice.