The analysis of MRI findings and prognosis in meconium peritonitis prenatal / 实用放射学杂志

Objective To discuss the prenatal MRI features and the fetal outcomes of meconium peritonitis (MP).Methods The clinical data of 23 cases with MP were collected.The prenatal MRI features and fetal outcomes were analyzed retrospectively.Results Prenatal MRI features included meconium peritonitis pseudo-cyst (9/23,39.1%),fetal ascites (23/23,100.0%),bowel dilatation (9/23,39.1%), meconium leakage (3/23,13.0%),scrotal effusion (2/23,8.7%)and polyhydramnios (2/23,8.7%).Of the 23 fetuses,2 were induced and 2 1 were delivered.In 2 1 neonates,7 cases received surgical treatment,1 3 cases received conservative treatment and 1 case was dead due to treatment refusal of the family.Neonates with bowel dilatation and meconium leakage all underwent surgery,neonates with meconium peritonitis pseudo-cyst and fetal ascites underwent conservative treatment,and the rate of operation was 100%,100%,22.2% and 35.0%,respectively. Conclusion Prenatal MRI findings of MP are characteristic.Bowel dilatation,meconium leakage,growing meconium peritonitis pseudo-cyst and meconium peritonitis pseudo-cyst connectted with adjacent intestine are highly suggestive of early surgical intervention in neonate.

The MRI diagnosis of infant brachial plexus injury / 实用放射学杂志

Objective To evaluate the value of MRI in diagnosis of brachial plexus injury in infants.Methods MRI manifestations and electromyography(EMG) data of 14 cases were analyzed retrospectively.Kappa statistic was used to analyze the consistency between the two methods.Results Pure preganglionic injuries were found in 5 cases,preganglionic and postganglionic combined injuries occurred in 9 cases.MRI features of preganglionic injuries include:absence of roots in spinal canal (7 cases),nerve root enlargement (1 case),nerve sleeve dilation (3 cases),pseudomeningoceles (5 cases) and the dura thickening (3 cases).MRI features of postganglionic injuries include:trunk thickening with hyperintensity in STIR images(14 cases),adjacent structure disorder and edema (1 cases).The consistency of MRI and EMG was good (κ=0.752,P＜0.05).Conclusion MRI is an efficient method for demonstrating preganglionic and postganglionic injuries,and can provide reliable information for early diagnosis and treatment for brachial plexus injury in infants.

The value of MRI texture analysis based on gray level co-occurrence matrix to predict cervical lymph node metastasis in tongue carcinoma patients / 中华放射学杂志

Objective To evaluate the value of MRI texture analysis based on gray level co-occurrence matrix to predict cervical lymph node metastasis in patients with tongue carcinoma. Methods A total of 70 patients with tongue carcinoma confirmed by pathology were analyzed retrospectively. The patients were divided into cervical lymph node (LN) metastasis group (unilateral LN+, n=18;bilateral LN+,n=22) and no cervical lymph node metastasis(LN-,n=30). T1W, T2W and contrast-enhanced T1W images of the largest section of tumor were selected. ROI of the lesion was manually drew and GLCM texture parameters (energy, contrast, correlation, inverse difference and entropy) were extracted. The tumor length, thickness and para-lingual distance between tumor and tongue midline were also measured.Differences of all parameters were compared between LN+ group and LN- group, unilateral and bilateral cervical lymph node metastasis group, the parameters with statistically significant difference in predicting the efficiency of cervical lymph node metastasis were analyzed. The diagnostic efficiency of lymph node metastasis was calculated. Results The correlation, inverse difference and entropy based on T2WI showed significant difference (Zcor elation=2.97, tinverse dif erence=5.14, tentropy=2.41; P<0.05), entropy showed the best diagnostic efficiency, the area under the ROC curve (AUC) was 0.90, the cut off value was 7.19, the sensitivity was 80.0％, specificity was 86.7％. Only entropy showed significant difference between unilateral LN+group and bilateral LN+group (P<0.05), the AUC was 0.82, the cut off value was 7.47, the sensitivity was 90.9％, specificity was 78.8％. The index of tumor length, thickness and para-lingual distance between tumor and tongue midline all showed significant difference between LN+group and LN-group (P<0.05), the thickness showed the best diagnostic efficiency, the AUC value was 0.81, the cut off value was 11.19, the sensitivity was 78.0％, specificity was 81.7％. The index of tumor length, thickness and para-lingual distance between tumor and tongue midline showed no significant difference between unilateral LN+ group and bilateral LN+ group (P>0.05). The diagnostic sensitivity of radiologists was 65.0％ (26/40), the specificity was 80.0％ (24/32) on cervical lymph node metastasis. Conclusion Texture analysis based on T2WI can predict cervical lymph node metastasis in patients with tongue carcinoma. Entropy has certain value in predicting bilateral cervical lymph node metastasis.

MRI in diagnosis of Herlyn-Werner-Wunderlich syndrome / 中国医学影像技术

Objective To assess the value of MRI in diagnosis of Herlyn-Werner-Wunderlich syndrome (HWWS).Methods MR images of 10 patients with HWWS confirmed surgically and pathologically were analyzed retrospectively.The classification of HWWS on MRI was discussed.Results The 10 patients were included 4 cases of type Ⅰ,3 cases of type Ⅱ and 3 cases of type Ⅲ.All of them were complicated with ipsilateral renal agenesis.Eight cases were complicated with didelphic uterus and double cervix,2 were complicated with complete septate uterus.Type Ⅰ showed the complete oblique vaginal septum,hematocele in the oblique septum cavity and contralateral uterine cavity.Type Ⅱ showed the oblique septum cavity was connected with main vaginal through the hole of septum.Type Ⅲ showed the oblique septum cavity was connected with main vaginal through the cervical fistula.The prognosis were good in 8 patients.One patient occured obvious dysmenorrhea postoperation and MRI reminded right ovarian endometriosis cyst.One patient occured gusty hypogastralgia,and MRI reminded pelvic inflammation.Conclusion MRI can definitely diagnose and classify HWWS,and can provide useful information in the treatment of HWWS.

Radiological Features of Bronchopulmonary Dysplasia in Premature Infant / 实用放射学杂志

Objective To describe radiological features of bronchopulmonary dysplasia(BPD) in premature infants,and improve the diagnostic ability of BPD.Methods Eleven Premature infants with BPD underwent series of chest radiographs,X-ray features of BPD were analysed.Results The radiographic findings frequently included diffuse opacities,linear-reticular opacities,sacculiform radiolucent areas and over-inflation of lung.There were 4 cases with two of the radiological abnormalties obove,diffuse opacities and linear-reticular opacities in 2,diffuse opacities and sacculiform radiolucent areas in one and diffuse opacities and over-inflation in one.There were two cases with three kinds of X-ray features,including diffuse opacities,linear-reticular opacities and sacculiform radiolucent areas.There was one case with all of the radiological features noted above.Conclusion The chest radiographs appearance were of characteristics in premature infants with bronchopulmonary dysplasia.

Postpartum MRI appearance of placental implantation abnormality / 第二军医大学学报

Objective: To explore postpartum MRI appearance and diagnostic value of MRI for placental implantation abnormality (PIA). Methods: Postpartum MRI findings of 11 PIA patients (mean age:28?4.5 years; range 23-25) were analyzed retrospectively. All patients underwent hysterectomy because their placentae were not discharged spontaneously, the postpartum hemorrhage added up to 800-4 500 ml and PIA was diagnosed by MRI 2-6 d after delivery. Results:Compared with the signal of the outer layer of the myometrium on the same scanning sequence, the placental signals appeared isointense or slightly hyperintense and the dividing line between the placenta and uterine wall was indistinct on T_1WI. On T_2WI the placental signal intensity was higher than that of the uterine wall. Placenta accreta showed that the placenta was confluent with the uterine wall and the junctional zone continued and the thickness of junctional zone was normal or slightly thinning. Placenta increta showed that the placental tissue invaded the myometrium in the shape of “triangle”, “nodule” or “mushroom”, and the junctional zone became thinner locally or discontinued. On Gadolinium-enhanced T_1WI, the intensity of placental enhancement was higher than that of uterine wall and the placental tissue was confluent with the uterine wall. The surgico-pathologic examination found 7 cases of placenta accrete and 4 cases of placenta increta. MRI diagnosis showed 8 cases of placenta accreta and 3 cases of placenta increta. There was one misdiagnosis by MRI. Conclusion: MRI is an ideal tool for postpartum diagnosis of PIA and can accurately evaluate placental configuration, the extent of placental accreta and the location and deepness of placental invasion.

Correlation of nuclear DNA contents and p53 protein expression with CT image and prognosis of patients with epithelial ovarian tumors / 第二军医大学学报

Objective:To observe the nuclear DNA contents and expression of p53 protein in epithelial ovarian tumors(EOT) and to explore their correlation with CT images and prognosis in EOT patients.Methods: The nuclear DNA contents,expression of p53 protein and CT findings of 88 EOT patients were analyzed.Twenty-six EOT patients were followed up and were divided into AT group(aneuploid,n=19) and DT group(diploid,n=7) according to DNA ploid,and into p53 protein(+) group(n=15) and p53 protein(-) group(n=11) according to expression of p53 protein.The correlation of nuclear DNA content and p53 protein expression with CT findings and prognosis of EOT patients was analyzed.Results: The DNA index,patient number with AT and protein p53(+) rate were significantly different between patients with their cystic wall thickness≥3 mm and