Narrative Review of Nimesulide in Adults: Current Scenario

Nimesulide, a nonsteroidal anti-inflammatory drug (NSAID), has been used as an effective treatment regimen for patients aged >12 years for fever, acute pain, acute tendinitis, osteoarthritis and dysmenorrhea. It is reported to be a superior antipyretic and anti-inflammatory drug than paracetamol and aspirin, respectively, and is equal to any of the NSAIDs alone in terms of analgesia. This paper reviews the current scenario of nimesulide in adult patients, concerning clinical evidence, use in special population and expert opinion. Overall, in comparison to other NSAIDs, including coxibs, nimesulide has a promising overall efficacy, safety and tolerability profile, as well as a satisfactory benefit/risk evaluation.

“Society, Stress, and Doctor’s Suicides”: It is not only Dr Archana Sharma; you could be the next!

The changing scenario between society’s lookout toward the medical profession has taken a bad turn. The stress of education, practice starting, increasing to a peak of one’s performance in the early years and later on to maintain it after the age of 50 is a great challenge. Recent tragic events have brought up the role of social elements, media, press, politicians, police, and prosecutors under the lens. We as professionals and organizations must find out the weakest link which enforces someone to indulge in self-harm. We also should try to strengthen the chain of healthcare delivery system with the motto of “A healthy physician only can impart quality healthcare. His image, interests, and intentions must be protected by our own profession, society, policymakers— government agencies.” Doctor–patient relationship has always been the foundation of healthcare system. Since the times of Hippocrates, relationship of doctor–patient has been extensively debated, receiving attention pertaining to its sociological, literary, and philosophical aspects. At present, doctor–patient–society relationship is undergoing a progressively dangerous phase of distrust leading to increased violence against doctors. Especially after the spread of coronavirus disease pandemic in December 2019 (COVID-19), giving an altogether new dimension to it. The tragic suicide of Dr Archana Sharma has brought doctor–patient relationship into focus, whether positive? Or negative? Who is to decide? Over the last 2 decades, the trust which was gained over centuries and cultivated the relationship of doctors and their patients has started eroding and has been demonized during COVID-19 pandemic outbreak.