RESUMO
Background: Coronavirus disease 2019 (COVID-19) is a highly contagious viral illness caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). It has a catastrophic effect on the world resulting in more than 25 million deaths worldwide. In India on 30th January 2020 rst positive case in a student from Kerala of the SARS-CoV-2 infection. The SARS-CoV-2 can cause serious clinical complications, especially in elderly patients and in those with co-morbidities, especially diabetes obesity; cancer and digestive, endocrine, nervous and respiratory systems pathologies. The elevated biomarkers level was noticed in severe COVID 19 cases compared to non-covid 19 patients, revealing that D-dimer, CRP, ferritin, LDH, are signicantly correlated to COVID-19 severity. This review study aims to identify the most effective biomarker among C- reactive protein, IF6, D-dimer and ferritin to predict disease severity. This review intends to outline the biochemical laboratory tests that are useful in disease monitoring and assessment of severity in conrmed cases of COVID-19.