RESUMO
In Ayurveda all skin diseases have been described under Kustha. As per Charak samhita Chikitsasthana 7 Psoriasis observed to have same signs and symptoms, so correlated with Ekakustha. Psoriasis seemingly emerged from Greek word ‘Psora’ means ‘itch’. Psoriasis is a non infectious chronic relapsing inflammatory skin disease having unknown etiology, characterized by well defined dry scaly erythymatous patches with itching and covered with adherent silvery white scales. Panchkarma (Shodhana) is an Ayurvedic detox for Psoriasis which is complete cleansing and rejuvenating therapy for body mind and consciousness. Panchkarma (Shodhan) i.e. body detoxification is first step towards Psoriasis healing, unless the toxins are eliminated and body is cleansed healing process doesn’t begin. The present study was conducted on a 23 year old male having signs & symptoms of Psoriasis was selected & Pachan was done by Triphala, Musta, Sunthi followed by Snehapan with Panchtiktaguggulu Ghrita & then Virechan given with Haritaki churna, Katuki churna. It is found that Sodhan Karma in Psoriasis in terms of upper & lower limb scaling especially. External application also play a great role in treating psoriasis but its effective rate is higher if done after the Sodhan of the body. The present article reviews the concept of Psoriasis in Ayurveda and role of Shodhan in management of Psoriasis.
RESUMO
Objective: To compare serum lipid profile in different ultrasonographic grades of non alcoholic fatty liver disease [NAFLD]
Study Design: Cross sectional study
Place and Duration of Study: PNS SHIFA hospital, Karachi, from Oct 2015 to Jul 2016
Material and Methods: Seventy three adults of either gender were consecutively inducted after diagnosis of non alcoholic fatty liver disease [NAFLD] on ultrasonography [USG]. These individuals were further classified into grade I, II and III of NAFLD depending on US findings. Fasting blood sample of all the subjects was analyzed for serum fasting lipid profile comprising of total cholesterol [TC], triglycerides [TG], high density lipoprotein cholesterol [HDL-C] and low density lipoprotein cholesterol [LDL-C]. Serum non HDL cholesterol [nonHDL-C] was calculated by subtracting HDL-C from TC
Results: Among 73 subjects with NAFLD, 42.5%, 37% and 20.5% had grade I, II and III NAFLD respectively. All parameters showed significant increase in frequency of abnormal results with increasing grade of NAFLD except TG. Significant difference was found in mean TC [p=0.000], LDL-C [p=0.000], HDL-C [p=0.005] and nonHDL-C [p=0.000] between grades of NAFLD. Post hoc analysis revealed that only mean nonHDL-C was significantly different amongst all the grades of NAFLD
Conclusion: The increasing severity of NAFLD was found associated with increased frequency of dyslipidemia. Though most frequent dyslipidemia in NAFLD was low serum HDL-C followed by hypertriglyceridemia, only serum nonHDL-C was statistically different amongst all the grades of NAFLD