A Case of Gastric Teratoma Combined with Congenital Syphilis

Gastric Teratomas are exetremely rare in infancy and childhood. About 50 cases of gastric teratomas are reported in the world's literature. Most of them were male. Few were dignosed prior to surgery. The mos thelpful diagnostic aid was of teeth or bone in radiologic examinations. Treatment is surgical excision and all of them were benign. Recently, we experienced a case of gastric teratoma combined with congental syphilis which was confirmed by explo-lapa and biopsy in 2month old male infant, who had large intraabdominal mass, vomiting, respiratory distress and skin lesions. The literature on this subject was reviewed briefly.

Allogenic bone marrow transplantation in rabbit

No abstract available.

Clinical Study on Spina Bifida and Cranium Bifidum

Spina bifida or cranium bifidum result from a failure in fusion of skull(cranium bifidum) or the vertebral column(spina bifida). These entities are the most common anomalies of the nervous system which are associated with major abnormalities of cellular migration, and secondary mechanical deformities of the nervous system. During the last 12 years from Jan. 1967 to Dec. 1978, 83 cases of spina bifida and cranium bifidum had been admitted to the department of Pediatrics, Severance Hospital and evaluated clinically. Literature review were also made birefly.

Clinical Analysis of Cord Serum Immunoglobulin M

Determination of the immunoglobulin M(IgM) in umbilical cord sera has been advocated as a screening test for intrauterine infection, since the IgM is produced by the fetus and is not transported across the placenta from mother. The low level of IgM in normal neonate is thought to reflect the infrequent encounter of antigenic stimuli by the futus, upon exposure to an appropriate antigen, however, the fetus is capable of increased IgM production, as has been doucumented in infant with rubella syndrome, cytomegalic inclusion disease, toxoplasmosis and syphilis. But until now we don't have the normal value of cord serum IgM in Korean neonate yet. So we performed the study to determine the normal value of serum IgM in Korean neonate and further more we try to compare the value of other condition such as congenital syphilis, maternal infection during pregnancy other than syphilis and congenital anomalies. Results were as followes: 1. Normal value of cord Igm was 11.83+/-9.92 mg % 2. There was no sexual difference 3. Lowest levele were noted at small weight(2500 gm upwards arrow) and short gestation period(28 wk upwards arrow) but not significant thereafter 4. There was no difference by matenal age and socioeconomic status 5. In congenital syphilis there was significant increment of cord IgM compared with normal group 6. There was no significant increment of cord ISM in cogenital anomalies 7. After 6 months, IgM levels were increased to adult level.

Clinical Observation of Hemolytic Anemia in Children Except Isoimmunization

No abstract available.

Tuberculous Abscess and Empyema of the Liver

We have experienced a case of tuberculous abscess of the liver with empyema in a 12 years old boy. He was admitted with the chief complaints of pain and mass in the right upper abdomen of about 1 month duration and intermittent mild fever for 15 days. On examination, liver was palpable 5 cm below the right costal margin, and was tender and firm. Liver scan showed a cold area in the right posterior upper part of the liver. With the needle aspiration of the liver, 240 ml of yellowish-green pus was aspirated. The stained smears of the pus showed a large number of acid-fast bacilli, and the culture revealed a growth of Mycobacterium tuberculosis. Our patient was cured successfully by the drainage of pus with the needle aspiration of the liver and antituberculous medication. We have presented here a rare case whose the diagnosis was made without the help of any operative procedure, and reviewed the literatures.

Two Cases of Cri Du Chat(5p-) Syndrome

We have experienced two cases of the Cri Du Chat Syndrome. The first case, 1 and 11/12 year old female, was admitted to evaluated profound mental retardation and failure to thrive. The other, 3 month old female, visit this dept for cat-like cry. They had the typical clinical characteristics of the Cri Du Chat Syndrome and showed showed the classical chromosome abnormality (46, XX 5p-), revealed by cytogenetic study.

Cluster of Guillain-Barre Syndrome

Of 7 cases of Guillain-Barre syndrome reviewed, which was admitted to the Department of Pediatrics Yonsei University, College of Medicine during 3 months period from July through September 1980, serologic surveys for an infectious agent were found to be without demonstrable causes such as cytomegalovirus and measles virus. We reviewed 87 acses of Guillain-Barre syndrome, which was admitted to our hospital during 10 years from January 1970 through December 1979. In age incidence, 57% of patients were under 5 years of age. Males were affected more often than females; the ratio was 2:1. In seasonal incidence, 59% of patients occured in summer time.

A Case of Acute(infantile) Gaucher's Disease

A case of Acute infantile form of Gaucher's disease in Korean infant is described. The large cells characteristically found in the bone marrow and liver in Gaucher's disease have been investigated with electron microscope, as well as light microscope. The pertinent literature has reviewed briefly concerning the clinical and laboratory fingings, roentgenographic picture, pathogenesis, pathology, diagnosis and treatment of this disorder.

Histiocytic Medullary Reticulosis in childhood Report of Three Cases

Three cases of hisiocytic medullary reticulosis occurring in children aged 6 years, 9 years and 14 years, are described. In all children the diagnosis was based on anemia, granulocytopenia, thrombocytopenia and marked erythrophagocytosis by bone marrow and lymph node atypical histiocytes. They all showed immediate remission with combined chemotherapy of vinblastine and prednisolone, but Case 1 eventually died at 6 months after onset of this rapidly progressive, fatal illness and Case 2, 3 are alive 14 months after onset of their illness.

Congenital Toxoplasmosis

No abstract available.

A Clinical Study of Wilms' Tumor with Special Reference to the Cure Rate by Multimodality Treatment

Wilms' tumor is the most common intra-abdominal malignant tumor of childhood. There has been a progressive improvement in the over all survival rate of children with Wilms' tumor since the introduction of radiotherapy and nephrectomy. Survival has continued to improve with the addition of chemotherapy, initially actinomycin D, and later vincristine. This paper reviewed 34 patients with Wilms' tumor seen between 1965 and 1979 with special references to the significant factors in diagnosis as well as the influence of age, stage of disease and treatment on the prognosis. The usefulness of three modalities of treatment was discussed. A cure rate of 64.9% in the intensive multimodaliy treatment group was calculated by the Life Table Method.

Emergencies in Hemophilia

9 classic hemophilacs in Severance Hospital, Yonsei University from Dec. '77 to Aug. '79 were reviewed and analysed and the following results were obtained. 1. Intracranial hemorrhage is required the most immediate emergent therapy in hemophiliacs and computerized transverse axial tomogarhy may be essential for the accurate and noninvasive diagnosis and for the effective emergency treatment. 2. To conserve supplies of therapeutic materials and to decrease the possibility of transmitting hepatitis and other diseases with blood products, it is desirable to reduce the amount of blood products with the use of epsilone aminocaproic acid, and epsilone aminocaproic acid may be useful in extraction and/or other non-dental injury with hemophiliacs.

A Prospective Study of Development of Splenic Reticuloendothelial Function in Premature and Term Infants

No abstract available.

Liver Abscess in Childhood

We have presented an analysis of cases of liver abscess from the record of the Department of Pediatrics, Yonsei medical College, during the 10 year 8 months period from Jan. 1969 through Sept. 1979. The incidence of admission in pediatric was 0.05025%. There was male preponderance. The most frequently encountered symptoms and sings were fever and chill, anorexia, hepatomegale, pain and tenderness on right upper quadrant of abdomen. The pathogenetic mechanisms were lodgement in the liver of hematogenously dissemination, ascending infection of cholangitis, trauma. Cryptogenic liver abscess was seen in two cases. There were 5 cases of pyogenic liver abscess and 3 cases of amebic liver abscess. Undetermined etiology was noted in 2 cases. Roentgenography including scan is the most helpful diagnostic tool available. Only one patient with post-traumatic liver abscess was expired.

A Case of Infantile Polycystic Kidney confirmed by C-T Scan

A case of infantile polycystic kindney disease confirmed by computerired tomoraphy in a newborn female infant was reported with a brief review of references.

A Case of Achondroplasia

Achondroplasia is a rare disease and characterized by the combination of short extremities with an enlarged head and a trunk approximating normal size. We had experienced 4 cases of achondroplasia; they all showed stunted growth, short arms and legs, prominent forehead, flattening of the bridge of the nose and moderate degree of kyphcsis and one case was associated with hydrocephalus. X-ray showed the thickness of the bones and their irregular epiphyseal ends such as cupping, flaring and spurs. Intelligence seemed to be normal except one case. We had seen those patients at the age of 8 months, 6 months and 1year, 7months and 2 years, confirming achodroplasia by clinical, X-ray survey and biochemical study. Review of the references concerning achondroplasia was made briefly.