A case of Best's Vitelliform Macular Dystrophy

The authors experienced the Best's Vitelliform macular dystrophy in 77 year-old female. Ophthamoscopically, there was about 1.4 D.D. sized, slightly elevated, homogeneous yellowish egg-yolk like macular lesion with well defined brown pigmented margin in the left eye. Fellow eye had senile cataract and no fundus abnormalities except for mild inferior temporal branch retinal vein occlusion. Fluorescein angiography showed blockage of fluorescence in the vitelliform lesion and revealed no leakages or hyperfluolescences on perimacular area. Bilaterally, ERG showed normal findings. EOG revealed abnormally low light pead/Dark trough ratio.

Five Cases of Wegener's Granulomatosis with Ocular Manifestations

Wegener's granulomatosis is an uncommon disease characterized by necrotizing granulomatous lesions in the respiratory tract, generalized focal necrotizing vasculitis, and focal necrotizing glomerulonephritis. Ocular complications may occur secondary to contiguous granulomatous sinusitis or as a result of focal vasculitis and are encountered in 40 ~ 50% of cases of generalized form. We reviewed 5 cases of Wegener's granulomatosis which were confirmed by clinlcal findings and histopathologic examination of biopsy specimens, which revealed one or more ocular complications such as lid swelling, corneal degeneration, staphyloma, corneal ulcer, and nasolacrimal duct obstruction. The patterns of ocular disease, its relationship to systemic involvement, diagnostic method, and the response to therapy are discussed.