Malakoplakia in a Renal Allograft: A case report / 대한이식학회지

Malakoplakia is a rare inflammatory disease which usually involves the lower urinary tracts, especially in immunocompromised patients. The characteristic feature is parenchymal infiltration by macrophages, known as von Hansemann cells, and intra- or extracytoplasmic Michaelis-Gutmann bodies. We report a case of renal malakoplakia in a renal allograft patient. Renal allograft biopsy was performed 1.5 years posttransplantation under the impression of chronic rejection. By light microscopy, inflammatory infiltrate composed of many macrophages and Michaelis-Gutmann bodies were present in the renal medulla and accompanied by moderate tubular atrophy and interstitial fibrosis. (J Korean Soc Transplant 2001;15:256-258)