RESUMO
Sphenoid sinus mucoceles represent 1% of all paranasal sinus mucoceles. Patients with a sphenoid sinus mucocele often experience only ophthalmic symptoms such as visual impairment, diplopia and external ophthalmoplegia. The ophthalmic symptoms seem to be caused mainly by compression or inflammatory changes. CT scan and MRI help in the correct assessment of this lesion. We have experienced a rare case of optic neuropathy caused by sphenoid sinus mucocele which is likely to misdiagnose to optic neuritis. The mucocele was managed successfully by endoscopic marsupialization. We report this case with a review of related literature.
Assuntos
Humanos , Diplopia , Endoscopia , Imageamento por Ressonância Magnética , Mucocele , Oftalmoplegia , Doenças do Nervo Óptico , Neurite Óptica , Seio Esfenoidal , Tomografia Computadorizada por Raios X , Transtornos da VisãoRESUMO
BACKGROUND AND OBJECTIVES: Mast cells are widely distributed in the loose connective tissue and their predilection sites are the portals of entry into the host. It seems possible that mast cells play an important role in the eustachian tube as a gate of the middle ear cavity. The purpose of this study was to investigate the distribution of mast cells in the rat tympanic membrane and eustachian tube. MATERIALS AND METHODS: The tympanic membrane and eustachian tube of rats (5) were used in this study. The specimens of formalin-fixed paraffin-embedded tissues (4 micrometer) were observed by staining with toluidine blue. RESULTS: In the tympanic membrane mast cells were observed mainly just beneath the keratinizing stratified squamous epithelium of the tympanic membrane. Mast cells were also distributed in the connective tissue of the eustachian tube. Most of the mast cells were found adjacent to vessels and glands. The density of mast cells beneath the mucosal epithelium of the eustachian tube was significantly lower than that in deep connective tissue layer. Their presence in the eustachian tube was less prominent than in the tympanic membrane. CONCLUSION: It seems reasonable to suggest that mast cells in the tympanic membrane and eustachian tube are important in responding to continuous stimuli of the tympanic cavity.