A Case of Serologically Confirmed Ocular Toxocariasis with Peripheral Granuloma in a 34-year Old Woman

No Abstract Available.

The Clinicopathologic Characteristics of Lymphoid Tumor of The Orbit and Ocular Adnexa

The authors reivewed retrospectively the medical records and pathologic slides of 18 patients with the orbital lymphoid tumors that had been confirmed pathologically. Pathologic diagnoses were as follows : 14 cases of pseudolymphoma (benign reactive hyperplasia), 2 cases of atypical lymphoid hyperplasia and 2 cases of malignant lymphoma. Of the 18 patients, 7 cases were male and 11 were female. The average age at first visit was 53 years. Palpable or visible mass was the most frequent presenting symptom. There were no significant differences in clinical characterstics and radiologic findings between benign and malignant tumors. Determination of clonality of tumors by immunohistochemical study was useful method to differentate pseudolymphoma and atypical lymphoid hyperplasia from malignant lymphoma. An accompanying systemic disease was not found in all cases. All patients were received local orbital irradiation. Regression or disappearance of masses was noted in all cases. No patient have experienced recurrence or development of systemic disease during the mean follow-up of 30 month.

Electron Microsopic study of Diabetic Preretinal Membranes

We conducted electron microscopic observation of twenty diabetic preretinal membranes removed during vitrectomy. Membranes were composed of many different types of cells and vessels and intercellular substance. Vessels of develping stage had forming narrow lumen and endothelium showed pinocytic vesicles and apical microvilli, and surrounded with vascular pericytes and multilayed basement membrane. Vessels of mature stage had large lumen and endothelium was flat. In vessels of regressing stage, lumen was obstructed with plug of red blood cells and endothelial cells were degenerating with abundant residual bodies. Pericytes also showed degenerative change. Most of junctions between endothelial cells wer tight junciton in all stage of vessels, but incomplete form of tight junction with open intercellular cleft was found more frequently in vessels of immature stage. Cells found in membranes were fibroblast, macrophage, myofibroblast, fibrous astrocyte in frequency. Extravascular plasma cell and polymorphonuclear leukocytes were observed occasionally. Intercellular substance was lagely composed of mature collagen. These results suggest incomplete endothelial junctions may be partly responsible for permeability of diabetic new vessels, and degenerated endothelium and pericyte may contribute to vitreous hemorrhage.