Idiopathic granulomatous mastitis

The idiopathic granulomatous mastitis is a rare entity. Up till now there is no any theory that can explain this pathology, specially the auto-immune origin. So we can consider it as of unknown aetiology. It is often adopt a cancerous radio-clinical semiology, while the histological examination proves that it is of a benign nature. Its diagnosis depends on a multidisciplinary approach. It is of an exclusion diagnosis, which needs an adequate treatment, with a long course follow up. We report here a new idiopathic granulomatous mastitis case, through a review of literature, trying to present its epidemiologic and clinical aspects, discussing the diagnostical methods and the therapeutic difficulties

[ child's neuroectodermic melanotic tumors: one case report]

The child's neuroectodermic melanotic tumors represent a quite rare entity, and is often seen before the age of one year. Higher jaw bone represents the most frequented localization, followed by cranian localization. The histogenesis of the child's NMT has been debated for a long time. Thanks to molecular, histochemical, biochemical and ultrastructural studies, the neuroectodermic origin is admitted at present. The child's NMT prognosis remains unknown, they are considered as benign tumors although 10 to 15% of local recurrences, and 2 to 6% of malignant forms has been reported in literature. We report one case of the child's NMT of posterior cranian position in a four month infant being operated for a right occipital mass. Operatory fragment has been put through a morphological study coupled with an immunohistochemical marking [Cytokeratin, Vimentin, Membranary Epithelial Antigen]