Effects of Aqueous Extract of Some Selected Vegetables on Halofantrine Hepato-cardiatoxicity in Rats.

Aim: The protective effect of some selected vegetables {Moringa (Moringa oleifera), Cabbage (Brassica oleracea) and Tomato (Solanum lycopersicum)} against hepatocardio toxicity of halofantrine (an antimalarial drug) was evaluated in 72 albino rats. Study Design: The rats were grouped into eight of nine rats each. Three different doses; 7.1, 14.2 and 21.3mg/Kg of halofantrine were given to group II, III and IV respectively. Group V was co-administered with halofantrine and moringa extract 7.1 and 0.20mg/Kg respectively, Group VI co-administered with halofantrine and cabbage extract 7.1 and 0.10mg/Kg respectively, Group VII co-administered with halofantrine and Tomato extract 7.1 and 0.20mg/Kg respectively and Group VIII co-administered with halofantrine, moringa, cabbage and tomato extracts 7.1, 0.20, 0.10 and 0.20mg/Kg respectively). Group I was neither given the drug nor the vegetable extract serving as normal control. Methodology: The liver and heart function indices were evaluated using standard methods. Results: Serum liver enzymes, heart marker enzymes and concentration of malondialdehyde (MDA) were analyzed after 16, 96 and 192 hours of oral administration. Halofantrine administration caused significant increase (p<0.05) in the activities of all the enzymes with a peak at the 16th hour. Malondialdehyde had a peak at the 192 hours. The oral co-administration of vegetables extract showed a significant decrease (p<0.05) in the enzyme activities and concentration of malondialdehyde as compared sole administration of halofantrine. The result showed that Moringa, Cabbage and Tomato may have hepato and cardio protective effects against halofantrine toxicity. It may be concluded that consumption of vegetables may be beyond the nutritional needs but also for protective purposes.

Knowledge and attitudes toward child adoption and fostering among infertile women in northern Nigeria

Background: Infertility is a public health problem in the developing countries. However, the role of child adoption or fostering in the management of infertile couples is underexplored, particularly in northern Nigeria. Materials and Methods: A cross-sectional study involving the use of a structured interview questionnaire was employed to collect information from clients attending the infertility clinic of Aminu Kano University Teaching Hospital (AKTH), Kano. The data were analyzed using MINITAB® 12.21 software. Percentages and means were used to describe categorical and quantitative variables, respectively. The chi-square test was used to assess the significance of associations using a confidence interval of 95%. Results: Majority of the respondents (69.7%) were between 25 and 34 years of age, and of Hausa/Fulani ethnic group (79.6%). Knowledge of child adoption was good in 59.2% of the respondents, while the willingness to adopt versus foster was 28.2% and 44.4%, respectively. Conclusion: There is a need to advocate for infertility counseling services, so as to support infertile clients in taking informed decisions regarding child adoption or fostering as viable options for having their own families

Menstruation and menstrual hygiene amongst adolescent school girls in Kano, Northwestern Nigeria

This study examined the knowledge and practices of adolescent school girls in Kano, Nigeria around menstruation and menstrual hygiene. Data was collected quantitatively and analyzed using Epi info version 3.2.05. The mean age of the students was 14.4 ± 1.2 years; majority was in their mid adolescence. The students attained menarche at 12.9 ± 0.8 years. Majority had fair knowledge of menstruation, although deficient in specific knowledge areas. Most of them used sanitary pads as absorbent during their last menses; changed menstrual dressings about 1-5 times per day; and three-quarter increased the frequency of bathing. Institutionalizing sexuality education in Nigerian schools; developing and disseminating sensitive adolescent reproductive health massages targeted at both parents and their adolescent children; and improving access of the adolescents to youth friendly services are veritable means of meeting the adolescent reproductive health needs in Nigeria (Afr. J. Reprod. Health 2010; 14[3]: 201-207)

Occupational Hazard Perception and Utilization of Protective Measures by Welders in Kano City; Northern Nigeria

Background: Little is documented on welders' awareness of health hazards associated with welding in developing countries including Nigeria. This study assessed the perceived occupational hazards and adherence to safety measures among welders in Kano; northwestern Nigeria. Methods: A structured interview questionnaire was administered on a cross-section of 194 welders in Kano metropolis; and the data was analysed using SPSS 12.0 statistical software. Results: Overall; 58.8of the welders were aware of one or more workplace hazards. This was positively influenced by educational attainment; age and work experience. Of the 194 respondents; 86.1had experienced one or more work-related accidents in the preceding year. Only 34.5of welders used one or more types of protective device. Conclusions: The level of awareness of occupational hazards was high with low utilization of protective measures against the hazards. There is therefore need for safety education and legislation for the use of protective measures to safeguard workers health and increase productivity