RESUMO
A sinusite é uma causa rara de infecção intracraniana, sendo responsável por 2,4% dos casos em pacientes jovens, e tem como a complicação intracraniana mais frequente o empiema subdural (ESD). Descrevemos um caso raro de um adolescente imunocompetente de 16 anos que evoluiu com confusão mental, rebaixamento do nível de consciência, anisocoria, hemiparesia à direita, afasia e febre. Tomografa computadorizada confirmou ESD, e paciente foi submetido à avaliação laboratorial e abordagem clínico-cirúrgica para tratamento do quadro.
Sinusitis is a rare cause of intracranial infection, accounting for 2.4% of cases in young patients. The most frequent intracranial complication is subdural empyema (SDE). We describe a rare case of a 16-year-old immunocompetent adolescent who developed mental confusion, lowered consciousness, anisocoria, right hemiparesis, aphasia, and fever. Computed tomography confirmed SDE, and the patient underwent laboratory evaluation and clinical-surgical approach for treatment of the condition.
Assuntos
Humanos , Masculino , Adolescente , Empiema Subdural/diagnóstico , Empiema Subdural/etiologia , Sinusite Frontal/complicações , Sinusite Frontal/diagnóstico , Sinusite Frontal/tratamento farmacológico , Recidiva , Crânio/diagnóstico por imagem , Empiema Subdural/cirurgia , Tomografia Computadorizada por Raios X/métodos , Antibacterianos/uso terapêuticoRESUMO
The acid phosphatase in ungerminated conidia from Colletotrichum graminicola, a corn pathogen, was investigated using spectrophotometric and cytochemical methods. Acid phosphatase activity was studied in a homogenate obtained by fragmentation of ungerminated conidia. With p-nitrophenylphosphate as substrate, the apparent Vmax and Km were 1.000 nmol p-nitrophenol/mg of protein/min and 0.631 mM, respectively. The pH and temperature optima were 5.5 and 60 graus Celsius, respectively. A cytochemical ultrastructural assay showed deposition of the reaction product inside vacuoles but not extracellularly on the cell surface. The permeabilization of conidia with Triton X-100 increased acid phosphatase activity eight fold. Compared to other procedures, our method was fast, easy to perform and gave consistent results.