1.
Southeast Asian J Trop Med Public Health
;
1982 Dec; 13(4): 658-61
Artigo
em Inglês
| IMSEAR
| ID: sea-32613
RESUMO
The apparent partition coefficients (Papp.) of eight 4-aminoquinolines in 1-octanol/pH 7.4 buffered solutions have been determined and correlated with their reported antifilarial activities. Antifilarial activity appears to be present only in those 4-aminoquinolines which have log Papp. values falling within a narrow range of 2.8 to 3.2.