Effects of balanced diet associated with sports on the health of obese university students / Análise dos efeitos da dieta balanceada associada aos esportes na saúde dos estudantes universitários obesos / Análisis de los efectos de la dieta equilibrada asociada al deporte en la salud de estudiantes universitarios obesos

ABSTRACT Introduction The student, when entering university, is subject to new cycles and major changes in his routine, which includes exercise and nutritious habits. Objective Explore the effect of a balanced diet and physical exercise on the health of university students. Methods Through literature studies, a questionnaire was developed where the physical condition, nutritional habits, dietary structure, and exercise practice of obese college students were investigated and analyzed. Results The BMI index of those investigated exceeded the standard limit of BMI > 25. The longer the time of physical exercise, the more evident the difference between male and female students in terms of physical endurance factor. The body weight, BMI, and body fat index of both groups showed a downward trend after the intervention. Six weeks of aerobic exercise combined with a proper diet can significantly improve body mass index, body mass index, and physiological and biochemical indices of obese college students. Conclusion Balanced diet and exercise positively affect the health of obese college students. Level of evidence II; Therapeutic studies - investigation of treatment outcomes.

RESUMO Introdução O estudante, ao ingressar na universidade, está sujeito a novos ciclos e grandes mudanças em sua rotina, que inclui os hábitos de exercício e alimentares. Objetivo Explorar o efeito de uma dieta balanceada e exercícios físicos na saúde de estudantes universitários. Métodos Através de estudos da literatura, elaborou-se um questionário onde foram investigadas e analisadas a condição física, os hábitos alimentares, a estrutura alimentar e a prática de exercícios nos universitários com obesidade. Resultados o índice de IMC dos investigados ultrapassou o limite padrão de IMC > 25. Quanto maior o tempo de exercício físico, mais evidente é a diferença entre estudantes do sexo masculino e feminino no fator da resistência física. O peso corporal, IMC e índice de gordura corporal dos dois grupos apresentaram tendência de queda após a intervenção. Seis semanas de exercícios aeróbicos combinados com dieta razoável podem melhorar significativamente o índice de massa corporal, índice de massa corporal e índices fisiológicos e bioquímicos de estudantes universitários obesos. Conclusão Dieta balanceada e exercício físico possuem um efeito positivo sobre a saúde dos estudantes universitários obesos. Nível de evidência II; Estudos terapêuticos - investigação dos resultados do tratamento.

RESUMEN Introducción El estudiante, al entrar en la universidad, se ve sometido a nuevos ciclos y a grandes cambios en su rutina, que incluye el ejercicio y los hábitos alimenticios. Objetivo Explorar el efecto de una dieta equilibrada y el ejercicio físico en la salud de los estudiantes universitarios. Métodos A través de estudios bibliográficos, se elaboró un cuestionario en el que se investigó y analizó la condición física, los hábitos alimentarios, la estructura de la dieta y la práctica de ejercicio en estudiantes universitarios con obesidad. Resultados El índice de IMC de los investigados superaba el límite estándar de IMC > 25. Cuanto mayor es el tiempo de ejercicio físico, más evidente es la diferencia entre los alumnos y las alumnas en el factor de resistencia física. El peso corporal, el IMC y el índice de grasa corporal de ambos grupos mostraron una tendencia a disminuir después de la intervención. Seis semanas de ejercicios aeróbicos combinados con una dieta razonable pueden mejorar significativamente el índice de masa corporal, el índice de masa corporal y los índices fisiológicos y bioquímicos de los estudiantes universitarios obesos. Conclusión La dieta equilibrada y el ejercicio tienen un efecto positivo en la salud de los estudiantes universitarios obesos. Nivel de evidencia II; Estudios terapéuticos - investigación de los resultados del tratamiento.

Estimated economic burden of disease of Norovirus gastroenteritis of schools in the Pearl River Delta Region / 中国学校卫生

Objective@#This study aims to estimate the economic burden of disease of outbreak of norovirus gastroenteritis in the Pearl River Delta Region, and provide scientific evidence for the government’s decision-making and control measures.@*Methods@#Using a unified questionnaire, a survey was conducted to the schools and students’ families which had suffered an outbreak of norovirus gastroenteritis in the Pearl River Delta Region from October 2017 to April 2018.@*Results@#The survey found that the mean total economic burden of sick students was 720.41(95%UI=640.45-804.63)RMB. The mean economic burden of sick students who were inpatient, outpatient and self-treatment were 1 712.75(95%UI=328.50-34 00.00), 213.70(95%UI=191.83-236.33) and 58.97(95%UI=43.00-77.69)RMB, respectively. The mean economic burden of transport, extra tutoring and cost of lost labor were 53.63(95%UI=43.98-63.58), 558.49(95%UI=381.40-774.01) and 695.62(95UI=630.25-767.29)RMB. The mean total economic burden of health students was 382.62(95%UI=343.29-424.45)RMB. The mean total economic burden of school was 49 264.53(95%UI=22 363.38-79 976.25)RMB. The total economic burden of disease increases as the level of outbreak increases. The larger the epidemic level, the proportion of sick students’ financial burden gradually decreased, 56.58%,23.27% and 10.93%.@*Conclusion@#The high economic burden of disease of norovirus gastroenteritis in the Pearl River Delta Region, respectively, indicating that relevant departments should strengthen the prevention, control and education in order to mitigate the disease economic burden.

Retrospective evaluation and prediction of clearance and toxicity of high dose methotrexate in childhood acute lymphoblastic leukemia patients

To find the predictors of High Dose Methotrexate toxicities in childhood Acute Lymphoblastic Leukemia Patients. This study included 198 Childhood Acute Lymphoblastic Leukemia patients (303 infusions) who were treated with High Dose Methotrexate. Methotrexate levels at different time point were measured by modified enzyme multiplied immunoassay technique assay. The correlation between Methotrexate levels and toxicity was evaluated by Receiver Operating Characteristic curve. When the Methotrexate level at 42 h was lower than 0.76 µmol/L, the sensitivity for predicting thorough clearance at 66 h was 90.78%. When the Methotrexate level at 42 h was higher than1.5 µmol/L, the sensitivity for predicting delayed clearance was 82.17%. When the Methotrexate level at 66 h was higher than 0.5 µmol/L, the sensitivity for predicting Methotrexate toxicity was 89.09%. When the Methotrexate level at 66 h was lower than 0.1 µmol/L, the sensitivity for predicting Methotrexate nontoxicity was 92.73%. The Methotrexate level at 42 h could be predictor for delayed clearance. The Methotrexate level at 66 h could be predictor for toxicity.

Causes of misdiagnosis in assessing tubal patency by transvaginal real-time three-dimensional hysterosalpingo-contrast sonography

SUMMARY OBJECTIVE This study aims to investigate the causes of misdiagnosis in assessing tubal patency by transvaginal real-time three-dimensional hysterosalpingo-contrast sonography (TVS RT-3D-HyCoSy), in order to improve the diagnostic efficiency of TVS RT-3D-HyCoSy. METHODS A total of 162 oviducts of 83 infertility patients were examined by TVS RT-3D-HyCoSy. These results were compared with the gold standard for laparoscopic dye studies, and the misdiagnosed cases were analyzed. RESULTS TVS RT-3D-HyCoSy revealed that 68 oviducts were unobstructed and 94 obstructed. The results for the 144 oviducts were in line with the gold standard, while those for 18 oviducts were not. The accuracy rate of the TVS RT-3D-HyCoSy was 88.9%, and the misdiagnosis rate was 11.1%. The main causes of misdiagnosis included contrast medium countercurrent and diffusion, oviduct spasm, abnormal shape or position of the oviduct, pelvic adhesion, and poor imaging operation. CONCLUSION TVS RT-3D-HyCoSy can well-evaluate tubal patency, and understand and improve the cause of misdiagnosis. Furthermore, the diagnostic efficiency of TVS RT-3D-HyCoSy can still be further improved.

RESUMO OBJETIVO Este estudo tem como objetivo investigar as causas do diagnóstico equivocado na avaliação da patência tubária por meio da ultrassonografia de contraste histerosalpingo em tempo real transvaginal (TVS RT-3D-HyCoSy), a fim de melhorar a eficiência diagnóstica das TVS RT-3D-HyCoSy. MÉTODOS Um total de 162 ovidutos em 83 pacientes da infertilidade foi examinado por TVS RT-3D-HyCoSy. Esses resultados foram comparados com o padrão ouro para estudos de tintura laparoscópica, e os casos diagnosticados erroneamente foram analisados. RESULTADOS TVS RT-3D-HyCoSy revelaram que 68 ovidutos foram desobstruídos e 94 ovidutos foram obstruídos. Os resultados para os 144 ovidutos estavam em consonância com o padrão ouro, enquanto que aqueles para os 18 ovidutos, não. A taxa de acurácia do TVS RT-3D-HyCoSy foi de 88,9%, e a taxa de erro de diagnóstico foi de 11,1%. As principais causas de erro de diagnóstico incluíram contraponto e difusão do meio de contraste, espasmo do oviduto, forma ou posição anormal do oviduto, adesão pélvica e má operação de imagem. CONCLUSÃO TVS RT-3D-HyCoSy pode bem avaliar a patência tubária, e compreender e melhorar a causa do erro de diagnóstico. Além disso, a eficiência diagnóstica do TVS RT-3D-HyCoSy ainda pode ser melhorada.