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1.
Chinese Journal of Pathology ; (12): 27-31, 2011.
Artigo em Chinês | WPRIM | ID: wpr-295079

RESUMO

<p><b>OBJECTIVE</b>To study the clinicopathologic features and differential diagnosis of epithelioid sarcoma-like hemangioendothelioma (ES-H).</p><p><b>METHODS</b>The clinical, radiologic and pathologic features of three cases of ES-H were analyzed.</p><p><b>RESULTS</b>All the 3 cases occurred in male adults. The age ranged from 44 to 53 years. The presentations included left neck mass, iliac pain and bilateral shoulder masses. Histologically, ES-H was composed of a mixture of spindle and epithelioid tumor cells. Transition between the two cell types was demonstrated. The tumor cells were arranged in compact sheets, vague nodules or intersecting fascicles, amongst a collagenous stroma. Central coagulative necrosis was identified in one case, reminiscent the morphology that seen in epithelioid sarcoma. There was no evidence of angiogenesis, though focal presence of intracytoplasmic vacuoles was seen in one case, as in classic examples of epithelioid hemangioendothelioma. Immunohistochemical study showed that the tumor cells expressed both epithelial (AE1/AE3, CAM5.2 and epithelial membrane antigen) and endothelial (CD31, Fli-1 and factor VIII-related antigen) markers. Two of the cases were also positive for CD34. All of the patients were treated by surgical resection. Two patients remain well at 14-month and 9-month follow up, respectively. The remaining patient had repeated local recurrences during a 6-year period.</p><p><b>CONCLUSIONS</b>ES-H represents a rare morphologic type of hemangioendothelioma. It has some overlapping histologic features with epithelioid sarcoma and epithelioid hemangioendothelioma. The endothelial nature of ES-H is difficult to be verified on the basis of morphologic examination alone. Confirmation of the diagnosis with immunohistochemistry is necessary. ES-H is likely related to epithelioid hemangioendothelioma and may represent a cellular spindle cell variant of epithelioid hemangioendothelioma.</p>


Assuntos
Adulto , Humanos , Masculino , Pessoa de Meia-Idade , Antígenos CD34 , Metabolismo , Biomarcadores , Metabolismo , Diagnóstico Diferencial , Seguimentos , Hemangioendotelioma , Metabolismo , Patologia , Cirurgia Geral , Hemangioendotelioma Epitelioide , Metabolismo , Patologia , Ílio , Imuno-Histoquímica , Queratinas , Metabolismo , Metástase Linfática , Mucina-1 , Metabolismo , Pescoço , Recidiva Local de Neoplasia , Molécula-1 de Adesão Celular Endotelial a Plaquetas , Metabolismo , Proteína Proto-Oncogênica c-fli-1 , Metabolismo , Reoperação , Estudos Retrospectivos , Sarcoma , Metabolismo , Patologia , Cirurgia Geral , Ombro , Fator de von Willebrand , Metabolismo
2.
Chinese Journal of Preventive Medicine ; (12): 181-185, 2008.
Artigo em Chinês | WPRIM | ID: wpr-352490

RESUMO

<p><b>OBJECTIVE</b>To study the related risk factors of anemia of rural elderly women in Huangling county, Shanxi, northwest of China.</p><p><b>METHODS</b>Elderly women aged 50-75 years in Huangling (northwest of China) were selected as study objects. Finger hemoglobin (Hb) was measured and basic health survey was face-to-face questioned. Two-hundred anemia elderly women were entered into the case group; and by age-matching, 200 with normal Hb concentration were entered into the control group. Dietary survey, health and lifestyle questionnaire were undertaken, and related blood indexes were tested.</p><p><b>RESULTS</b>In case and control group, annual income was (446.1 +/- 107.9) vs (903.8 +/- 179.1) yuan (t = 3.06, P < 0.01), daily average physical active time was (9.6 +/- 3.2) vs (10.3 +/- 3.1) hours (t = 1.94, P < 0.05), proportion of experiencing food scarce period was 31.8% vs 22.6% (chi2 = 4.14, P < 0.05), waist circumference was (76.2 +/- 7.3) vs (79.5 +/- 8.9) cm (t = 4.08, P < 0.01), respectively; the total protein was (78.0 +/- 5.8) vs (81.9 +/- 6.0) g/L(t = 5.94, P < 0.01), serum iron was (13.9 +/- 5.7) vs (16.1 +/- 5.0) micromol/L (t = 4.19, P < 0.01), serum ferritin was (94.9 +/- 76.4) vs (116.6 +/- 85.2) microg/L (t = 2.58, P < 0.01), saturation of transferrin was 22.9% +/- 10.0% vs 25.6% +/- 8.7% (t = 3.16, P < 0.01), respectively. Multifactor conditioned logistic regression analysis showed that the odd ratio (OR) for anemia with annual income, whether experiencing food scarce period, daily average physical active time, staple food, soybean products, energy was 0.57, 4.74, 0.06, 0.59, 0.55, 0.65, respectively; their confidence interval (CI) was 0.45 - 0.71, 0.73 - 30.56, 0.01 - 0.52, 0.38 - 0.91, 0.34 - 0.87, 0.44 - 0.98, respectively.</p><p><b>CONCLUSION</b>The quality of diet, health status and related blood indexes in anemia elderly women were lower than those in control group; lower income, less active time, less staple food, soybean products and energy intake should be risk factors of anemia.</p>


Assuntos
Idoso , Feminino , Humanos , Pessoa de Meia-Idade , Anemia , Epidemiologia , Estudos de Casos e Controles , China , Epidemiologia , Inquéritos sobre Dietas , Hemoglobinas , Estado Nutricional , Fatores de Risco , População Rural , Inquéritos e Questionários
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