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1.
Artigo em Chinês | WPRIM | ID: wpr-1032663

RESUMO

Objective To evaluate Trousseau's test in the diagnostic value of subclavian artery stenosis. Methods Examining declining range of blood flow velocity (DRBFV) and recovery time of blood flow velocity (RTBFV) during systolic period of vertebral artery in 38 cases of SAS and 37 controls by TCD combining Trousseau's test. Results After Trousseau's test, the DRBFV were increased and the RTBFV were prolonged significantly in SAS groups compared with those of systolic vertebral artery in controls, which are related to the stenosis degree of SAS. Conclusion TCD combining Trousseau's test can improve the veracity in the diagnosis of SAS and evaluate the stenosis degree.

2.
Artigo em Chinês | WPRIM | ID: wpr-327329

RESUMO

<p><b>OBJECTIVE</b>To investigate the changes of nitric oxide concentration in the distal portion of a random pattern skin flap and the influence of the exogenous L-arginine on the survival of the random pattern skin flap.</p><p><b>METHODS</b>A random pattern skin flap (7 cm x 2 cm) was cranially designed and elevated on the back of a Wistar rat. An image analysis technology was used to evaluate the survival rate of the skin flap, while a biochemistry method was used to test the concentrations of the NO in the tissue.</p><p><b>RESULTS</b>The survival area of the flap in the L-arginine-treated group was significantly enlarged (63.83 +/- 5.13)% (P < 0.01) in seven days postoperatively, compared with the control group (43.26 +/- 2.86)%. The NO concentration in the tissue was no statistic difference between all of the groups immediately after the operation (P > 0.05). But, the NO concentration in the control was decreasing at the beginning and then increasing slightly to reach the high level in 12 hours after the operation. It was thereafter slumped down to the baseline in 72 hours after the surgery. Although the changes in the L-arginine-treated group were quite similar to the control excepting of the extent, the NO concentration was kept in a higher level in the sequential time after the operation (P < 0.01, P < 0.01, P < 0.05 and P < 0.01).</p><p><b>CONCLUSIONS</b>The NO concentration in skin flap tissue after the elevation was going up slightly for a short time. The exogenous L-arginine could promote the NO concentration in the random pattern skin flap to protect it from ischemic injury.</p>


Assuntos
Animais , Feminino , Masculino , Ratos , Sobrevivência de Enxerto , Óxido Nítrico , Usos Terapêuticos , Distribuição Aleatória , Ratos Wistar , Transplante de Pele , Métodos , Retalhos Cirúrgicos , Resultado do Tratamento
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