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Objective To evaluate the value of high-frequency color ultrasound for different types of thyroid nodules during healthy examinations. Methods A total of 150 subjects with ultrasound diagnosis of thyroid nodule abnormality were enrolled. The sensitivity, specificity, positive predictive value, negative predictive value and accuracy of ultrasound diagnosis for differentiating benign and malignant thyroid nodules were evaluated with histopathological examinations of surgical thyroid specimens as a gold standard. Results A single thyroid nodule was found in all patients, and histopathological examinations identified 102 benign thyroid nodules and 48 malignant nodules. Microcalcification showed the highest accuracy for prediction of benign and malignant thyroid nodules (98.1%; χ2 = 45.67, P = 0.001), followed by taller than wider shape of thyroid nodule (92.1%; χ2 = 34.06, P = 0.001), central vascularity (82.0%; χ2 = 13.29, P = 0.001), halo (76.0%; χ2 = 6.15, P = 0.008) and hypoechogenicity (70.3%; χ2 = 10.63, P = 0.001). In addition, ultrasound diagnosis showed a 100.0% sensitivity, a 94.1% specificity, a 88.9% positive predictive value, a 100.0% negative predictive value and a 96.0% accuracy for differentiation between benign and malignant thyroid nodules (χ2 = 41.830, P < 0.001). Conclusion High-frequency color ultrasound has a high diagnostic accuracy for differentiating benign and malignant thyroid nodules, and microcalcification and taller than wider shape of thyroid nodule exhibit high values for predicting the malignancy of thyroid nodules.
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Objective To explore the ginkgo biloba extract curative effect of treatment of elderly unstable angina.MethodsFrom January 2012 to December 2015 encounters during the period of 100 cases of elderly patients with unstable angina as the research object, they were dinided into two groups according to the different methods of treatment.Observation group and control group adopts western medicine aspirin enteric-coated metformin hydrochloride, isosorbide mononitrate zyban and combination treatment with atorvastatin calcium tablet.Observation group plus treated with ginkgo biloba extract tablets.ResultsObservation group the treatment of patients with total effective rate (94.0%) is significantly higher than control group (78.0%), the difference is statistically significant (P<0.05);Before the treatment, two groups product of systolic blood pressure, heart rate and heart rate in patients with systolic blood pressure, CRP index close, there was no statistically significant difference;But after treatment, the observation group of patients with indicators better, statistically significant difference (P<0.05);Blood lipid and blood rheology after treatment, the observation group improved significantly (P<0.05), but the control group to improve the situation is not obvious, the difference between groups with statistical significance (P<0.05);Two groups of adverse reactions in patients with no statistically significant difference.ConclusionGinkgo biloba extract in the treatment of the elderly unstable angina has significant clinical effect, can significantly improve the patient′s blood lipid and blood rheology indexes, and the safety of the drug is good.