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1.
Chinese Journal of Behavioral Medicine and Brain Science ; (12): 840-845, 2022.
Artigo em Chinês | WPRIM | ID: wpr-956168

RESUMO

Objective:To observe the effect of methylphenidate hydrochloride (MPH) combined with mentalization-based family therapy (MBFT) on clinical efficacy and social function in children with attention deficit hyperactivity disorder (ADHD).Methods:Sixty-four children with ADHD diagnosed in Wuxi Children's Hospital and Affiliated Hospital of Jiangnan University from June 2019 to May 2021 were selected and divided into observation group ( n=32) and control group ( n=32) according to the random number table.Children in both groups received methylphenidate hydrochloride extended-release tablets, while those in the observation group were given additional MBFT.The duration of treatment was 12 weeks in both groups.The parent symptom questionnaire (PSQ), swanson nolan and pelham-version Ⅳ (SNAP-Ⅳ) parent Al scale, and Weiss impairment functional scale (WFIRS-P) were used to evaluate the effectiveness of treatment.Statistical analysis was performed by SPSS 25.0 statistical software.In particular, the χ2 test was used for counting data and the paired sample t test was used for comparison of measurement data between the two groups before and after treatment. Results:(1) All the PSQ dimension scores of patients in the observation group and the control group after treatment were significantly lower than those before treatment (all P<0.01). Compared with the control group after treatment, the PSQ dimension scores of personality and behavior problems ((1.25±0.15), (0.94±0.18), t=7.484, P<0.001), learning problems ((1.57±0.16), (1.32±0.20), t=5.522, P<0.001), psychosomatic disorders ((0.56±0.11), (0.44±0.13), t=3.986, P<0.001), impulse hyperactivity ((1.76±0.23), (1.54±0.25), t=3.663, P<0.001), anxiety ((0.94±0.12), (0.76±0.11), t=6.255, P<0.001) and hyperactivity index ((1.74±0.19), (1.51±0.16), t=5.238, P<0.001) decreased significantly in the observation group after treatment.(2) Compared with the pre-treatment period, the SNAP-Ⅳ scale scores of attention deficit, impulsivity-hyperactivity and oppositional defiance were significantly lower in both groups after treatment (all P<0.01); and compared with the control group, the SNAP-Ⅳ scale scores of the above three dimensions were significantly lower in the observation group (all P<0.01). (3) All six dimensions (family, learning and school, life skills, self-management, social activities, and risk-taking activities)of the WFIRS-P scale were significantly lower in the children in the observation group after treatment compared with those before treatment (all P<0.01), and all the six dimensions of the WFIRS-P scale were significantly lower in the observation group compared with those in the control group (all P<0.01). Conclusion:Methylphenidate hydrochloride extended-release tablets combined with MBFT can significantly improve the clinical symptoms and social function of children with ADHD.

2.
Chinese Journal of Behavioral Medicine and Brain Science ; (12): 925-929, 2019.
Artigo em Chinês | WPRIM | ID: wpr-791127

RESUMO

Objective To explore the mediating role of intelligence in the relationship between in-formation processing speed and numerical magnitude processing of hearing-impaired children. Methods A survey was conducted among 249 hearing-impaired children by using tests of Choice Reaction Time,Numero-sity Comparison,and Raven's Progressive Matrices( simplified version). Results (1) The accurate rate of information processing speed(0. 89±0. 18)of hearing-impaired children was positively correlated with that of numerical magnitude processing(0. 65±0. 15)and intelligence(11. 83±10. 34)(r=0. 165,0. 263,both P<0. 01). The reaction time of information processing speed was negatively correlated with those of numerical mag-nitude processing and intelligence(r=-0. 164,-0. 197,both P<0. 05). And there was significant positive correlation between intelligence and numerical magnitude processing (accurate rate and reaction time ) (r=0. 269,0. 140,both P<0. 05). ( 2) The accurate rate of information processing speed significantly predicted that of numerical magnitude processing in hearing-impaired children( β=0. 17,t=2. 64,both P<0. 01). The reaction time of information processing speed significantly predicted that of numerical magnitude processing in hearing-impaired children(β=-0. 16,t=-2. 61,both P<0. 05). And intelligence played a complete medi-ating role in this relationship and the moderating effect were 36. 71% and 31. 25%. Conclusion Information processing speed has indirect effects on numerical magnitude processing through intelligence in hearing-im-paired children.

3.
Chinese Journal of Behavioral Medicine and Brain Science ; (12): 925-929, 2019.
Artigo em Chinês | WPRIM | ID: wpr-796988

RESUMO

Objective@#To explore the mediating role of intelligence in the relationship between information processing speed and numerical magnitude processing of hearing-impaired children.@*Methods@#A survey was conducted among 249 hearing-impaired children by using tests of Choice Reaction Time, Numerosity Comparison, and Raven's Progressive Matrices(simplified version).@*Results@#(1)The accurate rate of information processing speed(0.89±0.18)of hearing-impaired children was positively correlated with that of numerical magnitude processing(0.65±0.15)and intelligence(11.83±10.34)(r=0.165, 0.263, both P<0.01). The reaction time of information processing speed was negatively correlated with those of numerical magnitude processing and intelligence(r=-0.164, -0.197, both P<0.05). And there was significant positive correlation between intelligence and numerical magnitude processing (accurate rate and reaction time ) (r=0.269, 0.140, both P<0.05). (2)The accurate rate of information processing speed significantly predicted that of numerical magnitude processing in hearing-impaired children(β=0.17, t=2.64, both P<0.01). The reaction time of information processing speed significantly predicted that of numerical magnitude processing in hearing-impaired children(β=-0.16, t=-2.61, both P<0.05). And intelligence played a complete mediating role in this relationship and the moderating effect were 36.71% and 31.25%.@*Conclusion@#Information processing speed has indirect effects on numerical magnitude processing through intelligence in hearing-impaired children.

4.
Chinese Journal of Primary Medicine and Pharmacy ; (12)2006.
Artigo em Chinês | WPRIM | ID: wpr-559525

RESUMO

0.05).The DPOAE incidence in sensorineural hearing loss group was 18%,compared with normal group and pseudo-anacousia group,the DPOAE incidence were significantly lower(P

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