Tromboembolismo pulmonar en lactante menor, portadora de enfermedad de Hirschsprung: caso clínico / Pulmonary thromboembolism in children with Hirschsprung disease: clinical case

Se presenta el caso de una lactante con enfermedad de Hirschsprung que requirió alimentación parenteral permanente y que presentó complicaciones de las vías venosas centrales incluyendo trombosis, septicemia y tromboembolismo pulmonar. El diagnóstico de las complicaciones trombóticas mediante Doppler y cintigrafía de ventilación perfusión permitió un tratamiento oportuno y seguimiento adecuado.

Osteopenia en cirrosis biliar primaria: estudio en 20 pacientes / Osteopenia in primary biliary cirrhosis: study in 20 patients

We studied 20 female patients, aged 51 ñ 13.6 years old, with the diagnosis of Primary Biliary Cirrhosis (PBC) to assess osteopenia, main involved sites and its relation to menopause, some parameters of mineral metabolism and the degree of histological liver involvement. The diagnosis of PBC was based in histological, clinical and laboratory features. Bone densitometry was measured with dual-photon densitometer and compared with values of a normal female population from the laboratory. When compared to controls, studied patients had a significantly lower lumbar spine bonedensity and total bone mineral content and a non significantly lower density in femoral neck and total body. Serum calcium, phosphorus, magnesium, PTH and urinary calcium/creatinine ratio were within normal limits. Lumbar spine density was no significantly lower in patients with more severe liver histological involvement and in postmenopausal women. No correlation was found between the duration of postmenopausal period and the degree of osteopenia. It is concluded that patients with PBC have a clear lumbar spine osteopenia and a lower total mineral content and that these parameters worsen in a non significant fashion in subjects along with liver histological involvement and with the length of post menopausal period

Demencias prefrontales: clínica y spect en seis casos / Prefrontal dementias: clinic and spect in 6 cases

Six patients with primary degenerative dementias and frontal or frontotemporal hipoperfusion are reported. Five were diagnosed as Frontal Progressive Dementia (FPD), characterized by striking changes in personality and social behavior. The last patient had a progressive aphasia and a moderate cognitive impairment. We discuss the heterogeneity of FPD that includes Pick's disease, frontal lobe type dementia (Neary) and progressive subcortical gliosis. The usefulness of Spect and the need of a brain bank are remarked

Agenesia de todas las glándulas salivales mayores asociadas con defectos del aparato lacrimal: estudio cintigráfico de un caso clínico / Agenesia of the major salivary glands associated with lacrimal apparatus defects: scintigraphic case study

Se presenta un caso de agenesia de todas las glándulas salivales mayores en una niña de 3 años y 4 meses de edad, demostrada mediante cintigrafía. Además de presentar alteraciones del aparato lagrimal asociadas, llama la atención la baja incidencia de caries encontrada, hecho que probablemente se debe a la corta edad de la paciente, motivo por el cual las xerostomía derivada de la ausencia de glándulas salivales aún no evidencia efectos manifiestos. Se destaca que de acuerdo a la literatura revisada correspondería al séptimo caso de agenesia de todas las glándulas salivales mayores publicado