Triangle of beauty of the face in Thai adults.

In order to evaluate the aesthetic triangle of the face in Tai adults, we measured the vertical nasal height and the lower facial height of 200 subjects by using the sliding caliper. There were 100 males and 100 females who had never had nasal surgery or severe nasal injury. Their ages ranged from 15-65 years old. The mean body height in males was 165.5 + 6.2 cms; in females, 155.4 + 5.2 cms; the mean body weight in males was 58.2 8.0 kgs; in females, 52.4. The study showed that the average vertical nasal height in males was 5.1 + 0.3 cms; in females, 4.8 + 0.3 cms; the average lower facial height in males was 6.6 + 0.4 cms; in females, 6.3 + 0.4 cms. Statistical analysis revealed significant differences of the two parameters measured between males and females. There was significant correlation between the lower facial height with body weight and body height only in Thai males.

A study on CNS-side effects of mequitazine, an H1-specific antihistamine in healthy Thai volunteers.

Mequitazine is a potent, non-sedative, long-acting H1-specific antihistamine proven to be a better therapeutic drug than other conventional antihistamines. It is also reported by many authors that the drug produces less sedative or other depressive actions on the central nervous system than other antihistamines. In order to evaluate the advantage of this drug in Asian people, an assessment of side effects of mequitazine, in comparison with chlorpheniramine, on the central nervous system was done in 20 healthy Thai volunteers, 10 males and 10 females 23-39 years of age, using a double blind crossover placebo controlled trial. Various subjective tests: alertness scale rating, visual analogue scale rating as well as objective tests: card sorting, glassbead picking and estimation of reaction time, were performed. There were no significant differences in side effects on the central nervous system between mequitazine and the placebo, whereas chlorpheniramine did produce side effects.

Study of the CNS side effect of loratadine, a new antihistamine.

Loratadine, a derivative of the known antihistamine, Azatadine has been proved to be scarcely distributed to the CNS, having high selectivity for peripheral histamine H1-receptore, hence lacking of CNS depressant effects. Lortadine is an effective antihistamine for the treatment of many allergic diseases. The authors have studied the CNS depressant effects of Loratadine in 35 normal Thai volunteers; 17 males, 18 females, age ranged 20 to 40 years, using a double blind cross over placebo controlled design comparing with chlorpheniramine. The test methods were both subjective and objective i.e. visual analogue scale, alertness rating scale, card sorting test, glassbead picking test, recording of the reaction time test for light stimulation. The CNS side effects of loratadine proved to be differ from those caused by placebo and significantly less than the CNS depressive effect by chlorpheniramine.