RESUMO
We reconstructed and compared 3D digital models of basal ganglia of human and rat. After selecing the sections con-taining basal ganglia from sterotoxic atlases of human and rat, 3D digital model of basal ganglia of human and rat was recon-structed by using general-purpose 3D modeling and animation software 3D Studio MAX and its 3D loft function. Several modifi-cation processes were done then to make the digital model more smooth. The 3D digital models of basal ganglia of human and ratwere successfully constructed and the comparative neuroanatomy study was conducted. The virtual reality technics was then in-troduced into this study, using internet browser, digitalized basal ganglia could be rotated, detached and resembled arbitrarily.Our study showed: (1) No matter on their morohology or their components, there were little differeces.(2) Due to ortho-statism, the rostro-caudal axis of human brain was rotated with certain angle, as the result, the relative positions among nucleiof human basal ganglia did differ from that of rat. (3) The projection fibers arrived the correspoding part of their target nucleiwith the shortest way, which might become the basis of the basal ganglia intrinsic topological projection.