Clinical Study of Three Trembling Needles for Early Parkinson's Disease / 上海针灸杂志

Objective To observe the clinical efficacy of needling the three trembling points plus rehabilitation and taking levodopaand benserazide hydrochlo-ride.Method Ninety-three patients with early Parkinson's disease were randomized into group A of 32 cases, group B of 30 cases, and group C of 31 cases. Group A was intervened by needling the three trembling points plus rehabilitation and taking levodopaand benserazide hydrochlo-ride, group B by rehabilitation and taking levodopaand benserazide hydrochlo-ride, while group C by taking levodopaand benserazide hydrochlo-ride. UPDRSⅢ scores and Berg balance scale (BBS) scores were observed.Result After intervention, UPDRSⅢ scores and BBS scores were significantly changed in all groups (P<0.05). UPDRSⅢ scores of group A were markedly different form that of group B and C (P<0.05). BBS scores of group A and B were markedly different form that of group C (P<0.05).Conclusion Needling the three trembling points plus rehabilitation and taking levodopaand benserazide hydrochlo-ride can improve motor function and equilibrium function in the early Parkinson's disease patients.

Analysis of the effect of the combination of radix salviae miltiorrhizaenovol-ten, diclofenac and soldium aescinate in treatment of severe migraine / 中国临床药理学与治疗学

AIM: To explore the treatment methods of severe migraine. METHODS: 51 cases of severe migraine patients were treated with the combination of radix salviae militiorrhizae, diclofenac and sodium aescinate, and another 62 cases of severe migraine patients were treated with diclofenac alone. RESULTS: The efficacy of the combination is better than that of diclofenac alone (P

Efficacy and safety of gabapentin in the treatment of migraine:a double-blind randomized placebo-controlled study / 中国临床药理学与治疗学

AIM:To evaluate the efficacy and safety of gabapentin in the treatment of migraine.METHODS:A randomized,double-blind,placebo-controlled study was taken.104 patients(aged 18 to 60 year)with migraine were randomly assigned to receive placebo(control group,49 patients)or gabapentin(experimental group,55 patients)for 4 weeks.The efficacy,side effects,TCD and EEG were assessed at the beginning of trials,and 4th,8th weeks.RESULTS:Comparing with the placebo group,the frequency,duration and intensity of migraine were markedly decreased in gabapentin group,there was significant difference between groups(P0.05).CONCLUSION:Gabapentin is an effective and safe agent from migraine.