Correlation of peritumor brain edema with proliferation of meningiomas / 中国基层医药

Objective To study the correlation of peritumor brain edema and the proliferation of meningiomas.Methods Forty-six patients who underwent resection of meningioma were divided into four groups(no,mild,middle and severe PTBE) according to CT.Proliferating cell nuclear antigen(PCNA) was detected with immunohistochemistry.Results There were 18 cases mild PTBE[PCNA LI (2.83?1.57)],10 cases middle PTBE[PCNA LI (3.14?2.04)] and 5 cases severe PTBE[PCNA LI (4.13?2.43)] in forty-six patients.PTBE was related to meningioma PCNA LI significant.Conclusion PTBE of meningioma relates with tumor cell proliferation.