RESUMO
Asprosin is a newly discovered fasting-induced glucogenic adipokine, which is involved in regulating appetite, glucose and fat metabolism and oxidative stress. Recently, it has been found that asprosin is related to metabolic diseases such as type 2 diabetes, obesity, nonalcoholic fatty liver, polycystic ovary syndrome, and cardiovascular diseases such as coronary heart disease and dilated cardiomyopathy, and plays an active role in heart protection. In this paper, the related research progress is summarized.
RESUMO
Ceramide is a kind of sphingolipid with complex function, which is involved in cell growth, differentiation, stress response, inflammatory signal transduction and apoptosis as a second messenger. In recent years, many studies have shown that it is closely related to the occurrence and risk prediction of cardiovascular diseases such as coronary heart disease, heart failure, atrial fibrillation, hypertension and so on. In this paper, the related research progress is summarized.