Vascular cognitive impairment with no dementia treated with auricular acupuncture and acupuncture:a randomized controlled trial / 中国针灸

<p><b>OBJECTIVE</b>To compare the clinical efficacy on vascular cognitive impairment with no dementia (VCIND) between the combined therapy of auricular acupuncture and acupuncture and the simple acupuncture.</p><p><b>METHODS</b>One hundred patients of VCIND were randomized into a combined therapy of auricular acupuncture and acupuncture group (a combined therapy group) and an acupuncture group, 50 cases in each one. The basic internal medicine treatment was applied in the two groups. Additionally, in the combined therapy group, auricular acupuncture and's three needling therapy were used. pizhixia (AT), xin (CO), shen (CO), gan (CO), erzhong (HX) were selected in auricular acupuncture, once every Monday, Wednesday and Friday;,andwere selected in's three needling therapy, once a day. In the acupuncture group,'s three needling therapy was just provided, once a day. The treatment was given for 4 weeks in the two groups. Montreal cognitive assessment (MoCA) and social function activities questionnaire (FAQ) were adopted for the evaluation comparison before treatment and in 2 weeks and 4 weeks after treatment in patients of the two groups.</p><p><b>RESULTS</b>Compared with those before treatment, the total scores of MoCA were improved in 2 and 4 weeks after treatment in the two groups (all<0.01). The score in the combined therapy group was improved more apparently as compared with that in the acupuncture group (<0.01). FAQ score was reduced in the two groups (all<0.05). The score in the combined therapy group was reduced more apparently as compared with that in the acupuncture group (<0.05). As compared with the result in 2 weeks of treatment, MoCA score was improved in the two groups in 4 weeks of treatment (both<0.01), the improvements in the combined therapygroup were more obvious than those in the acupuncture group (<0.05) and FAQ score was reduced in the two groups (<0.05), but the difference was not significant between the two groups (>0.05).</p><p><b>CONCLUSIONS</b>The combined therapy of auricular acupuncture and acupuncture effectively improve the cognitive function and social function, which are better than the effects of simple acupuncture in VCIND. The improvement of the combined therapy in social function is more advantageous in the treatment of the first two weeks.</p>

Evaluation of Clinical Efficacy of Heart and Spleen Deficiency Type Insomnia Treated by Acupuncture for Regulating Governor Vessel and Tranquilizing Spirit / 广州中医药大学学报

Objective To evaluate the clinical effect of acupuncture combined with estazolam for the treatment of primary insomnia with heart and spleen deficiency type. Methods Seventy qualified patients were randomized into treatment group and control group, 35 in each group. Both groups received oral use of estazolam before bed time for 6 continuous weeks, and acupuncture group was additionally given acupuncture for regulating governor vessel and tranquilizing spirit on acupoints of Baihui(GV20), Yintang(GV29), Shenting(GV25), Anmian (EX-HN22), Shenmen(H7), Sanyinjiao(SP6), 3 times a week and lasting for 6 continuous weeks. The sleep state of the patients was estimated according to Pittsburgh Sleep Quality Index (PSQI), Epworth Sleepiness Scale (ESS) and Athens Insomnia Scale(AIS) before treatment, on the third and the sixth week of treatment, and one month after the completion of treatment. Results (1) Five cases in the treatment group and 3 cases in the control group were dropped out for not completing the treatment timely. In the end , 30 cases in the treatment group and 32 cases in the control group finished the trial. (2) The total effective rate in the treatment group was up to 90.0%, and was 71.9% in control group, the difference being significant(P<0.01).(3) Compared to the control group, the scores of PSQI, ESS and AIS were much decreased in treatment group on the third and the sixth week of treatment , and one month after treatment(P<0 . 05 or P<0 . 01). Conclusion Acupuncture for regulating governor vessel and tranquilizing mind combined with oral use of estazolam exerts certain therapeutic effect for the treatment of heart and spleen deficiency type insomnia, and the effect was superior to that of estazolam alone.

Curing 1 Case of Adult Onset Still’s Disease with Chinese Traditional Medicine Plus Acupuncture Therapy / 浙江中医药大学学报

[Objective] Introduce 1 case of adult onset stil ’s disease cured by Chinese traditional medicine plus acupuncture therapy.[Methods] With TCM treatment we started from relieving shaoyang disorder, clearing heat and expel ing superficial evils, differentiated the case Shaoyang syndrome, then made a prescription of Xiao Chai-hu Tang and Qing-hao Bie-jia Tang to balance qi movement ,clear heat and expel dampness;with acupuncture treatment we discharged heat and expel ed wind at acute phase, supplemented the center and boosted the energy at stable phase. With the combined therapy that reached a total function of expel ing damp and regulating qi movement. [Results] The patient ’s symptoms relieved and discharged, fol owed the case 2 months without recurrence. [Conclusion] Chinese traditional medicine plus acupuncture therapy can cure adult onset stil ’s disease effectively, it is worth clinical application.

Progress of Clinical Study on Treatment of Hyperlipidemias with Acupuncture / 针灸推拿医学（英文版）

Objective: To summarize the clinical study on acupuncture treatment of hyperlipidemia for figuring out the existing issues and guiding the future study. Methods:Obtained by searching the scientific and technological journals database with computer, the relevant literature on acupuncture treatment of hyperlipidemia in the recent ten years is summarized and analyzed. Results and Conclusion: Forty-two pieces of the articles in conformity to the criteria of recruitment mainly refer to acupuncture, moxibustion, and simultaneous application of acupuncture and moxibustion, catgut-embedding method of the acupoints, external application of herbal products on the acupoints, and acupoint-injecting method, mostly by the acupoints of the Spleen and Stomach Meridians. But, the methods to select the acupoints by pattern identification, the application of the needling techniques and design of the test plans need to be further amended.

Effects of Acupuncture on Expression of Neurologic Factors in Hippocampus of Depression Rats / 广州中医药大学学报

Objective To observe the effect of acupuncture on brain-derived neurotrophic factor(BDNF) and nerve growth factor(NGF) expression in the hippocampus of depression rats,and to explore its possible anti-depression mechanism.Methods SD rats were randomized into the normal group,model group,acupuncture group and western medicine group.Rat models of depression were established by chronic unpredictable mild stress and by isolated raising.The western medicine group received gastric gavage of fluoxetine hydrochloride(in the dose of 2 mg?kg-1?d-1),and the acupuncture group received acupuncture on acupoints of Baihui(GV20),Xinshu(BL15) and Ganshu(BL17),once per day for 21 days.After treatment,the expression of BDNF and NGF in the hippocampus of rats was detected by immunohistochemical assay.Results The number of cells with BDNF and NGF positive expression in the hippocampus of model group was decreased(P

Clinical Observation of Jin's Three-needle Manipulation Combined with Rehabilitation Therapy for Treatment of Post-stroke Shoulder-hand Syndrome / 广州中医药大学学报

Objective To observe the therapeutic effect of Jin 's three-needle manipulation combined with rehabilitation therapy for post-stroke shoulder-hand syndrome(SHS).Methods Eighty-two post-stroke SHS patients were randomized into the treatment group(N =42) and the control group(N =40).The treatment group received Jin 's three-needle manipulation combined with rehabilitation therapy,and the control group received rehabilitation therapy alone.The pain score was evaluated with Visual Analogue Scale(VAS),the score of upper-limb function was evaluated with simplified Fugl-Meyer Assay,and the movement of shoulder joint was measured with conimeter.Results The pain was relieved,upper-limb function was improved,and the movement of shoulder joint was increased to some extent after treatment in both groups(P

Short-term Clinical Effect of Acupuncture Therapy for Vascular Dementia / 广州中医药大学学报

0.05 ). It is indicated that both eight extra-meridians acupuncture therapy and Jin Sanzhen therapy can improve intelligence index of VD, and the possible mechanism is related to the regulation of central nervous system function, elimination of SOD and reduction of NE and NO secretion.

Effect of Catgut Embedment in Acupoint on c-jun and bcl-2 Expression in Hippocampal Neurons of Rats with Status Epileticus / 广州中医药大学学报

[Objective] To explore the genetic mechanism of acupoint catgut embedment in inhibiting hippocampal neuron apoptosis in rats with status epileticus (SE). [Methods] Forty SD rats were randomized into 5 groups: blank control (A), model (B), dilantin (C), routine acupuncture (D) and acupoint catgut embedment (E). Rat models of SE were established by intra-abdominal injection of penicillin. With immunohistochemical method, the expressions of apoptosisrelated genes of c-jun and bcl-2 were observed in the vulnerable neurons of the hippocampus 24 hours after modeling. [Results] Compared with SE model group, the expression of c-jun was decreased and the expression of bcl-2 was increased in group C, D and E 24 hours after modeling; c-jun expression was positively related with the apoptotic index (AI) and bcl-2 expression was negatively related; the effects in group E much differed from those in model group. [Conclusion] The possible mechanism of the acupoint catgut embedment in treating epilepsy is related to the inhibition of the hippocampal neuron apoptosis by prohibiting the expression of c-jun and promoting the expression of bcl-2.

Treatment of Cervical Spondylosis of Vertebral Artery Type Mainly with Pressing - Moxibustion on Baihui Point (DU20): An Observation of 34 Cases / 广州中医药大学学报

[Objective] To observe the therapeutic effect of pressing- moxibustion on Baihui (DU20) point combined with electroacupuncture (EA) on cervical spondylosis (CS) of vertebral artery type. [Methods] A single - blind random - controll trial was carried out in 34 cases of CS of vertebral artery type. The cases were randomized into two groups: the treatment group (Group A, n = 17) treated with pressing- moxibustion on Baihui point and EA on bilateral Fengchi (GB20) point and Jiaji (EX - B2) point of impaired vertebrae and the control group (Gropup B, n = 17) with EA alone. Plasma contents of thromboxane 82 (TXB2), 6-keto-prostaglandin Fl alpha (6-keto-PGF1?) and their ratio were measured before and after treatment. [Results] In the treatment group, 9 were cured, 6 markedly effective, 2 effective and 0 ineffective and 4,6,5 and 2 in the control group respectively; the markedly effective rate was 88.2% which was superior to that (58.8%) in the control group (P

Influence of Jinsanzhen Therapy on the Motor Function and Activities of Daily Life of the Apoplectic Hemiplegia Patients / 中医杂志

Objective To evaluate the influence of Jinsanzhen therapy (A 3-point acupuncture method created by prof.JIN) on the motor function and activities of daily life of the apoplectic hemiplegia patients.Methods Totally 135 apoplectic hemiplegia patients were randomized into three groups:Jinsanzhen group,Rehabilitation group,and Jinsanzhen plus rehabilitation group,with 45 cases in each.The degree of hemiplegia motor function and activities of daily life of the patients was assessed with Fugl-Meyer assessment (FM) and Barthel index before,14 and 28 days after treatment.Results After 14 and 28 days' treatment,the FM value and Barthel index score of all the three groups are significantly increased (P