RESUMO
【Objective】 Digestive tract reconstruction after total gastrectomy is complicated and causes many complications. This study aimed to investigate the feasibility, safety and effectiveness of magnetic compression anastomosis (MCA) for sutureless reconstruction after total gastrectomy in rats. 【Methods】 Twenty-four rats were randomly apportioned to two groups. Reconstruction was performed with MCA in the experimental group or hand-sewn in the control group, and the construction time was recorded. The animals were followed up for 30 days. The survival rate and complications were monitored. At each time point, the rats were euthanized to study the gross/histological morphology and mechanical strength of the anastomoses. 【Results】 The reconstruction time was (12.9±2.7)min in the experimental group and (23.8±4.1)min in the control group (P=0.036). In the experimental group, there was no anastomotic complication. Four control rats developed anastomotic leakage or hemorrhage, and all died within 4 postoperative days. Compared with the control group, burst pressure in the experimental group was similar. Both groups’ anastomoses had smooth gross appearance and histologically good alignment of tissue layers. 【Conclusion】 MCA is a safe and effective choice for reconstruction after total gastrectomy, with better postoperative outcomes than hand-sewn.
RESUMO
Endoscopic submucosal dissection (ESD) is a mature method for treating early gastrointestinal tumors. Appropriate submucosal exposure is one of the important factors for the successful operation of effective and safe dissection. This article combines domestic and foreign literature to summarize the background, procedure, prognosis, characteristics and related clinical research of magnetic anchored-guided endoscopic submucosal dissection (MAG-ESD). Generally speaking, compared with traditional ESD, MAG-ESD can shorten the operation time, simplify operation steps, reduce the incidence of complications, and improve the learning curve. Compared with other traction technologies that assist ESD, magnetic anchor-assisted technology can be used in the whole digestive tract mucosal dissection to treat early-staged cancer. The operation has a better operation triangle, is less technically difficult, and is friendly to experienced endoscope operators. It is called the "second hand" of endoscope operators. It can greatly improve the clinical treatment efficiency and patient satisfaction of early gastrointestinal cancer.