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Chinese Journal of Virology ; (6): 464-471, 2008.
Artigo em Chinês | WPRIM | ID: wpr-334777

RESUMO

The N gene and genome promoter nucleotide sequence of a Chinese Peste des petits rumiants virus (PPRV) ("China/Tib/Gej/07-30") was firstly determined. The length of N gene was 1689 nucleotides with a single open reading frame (ORF). The nucleotide and deduced amino acid sequence was compared with the homologous region of other PPRV isolates. The nucleotide sequence of the "China/Tib/Gej/07-30" was 91.7%-97.6% identical to other PPRV isolates, while a homology of 94.9%-98.5% could be observed at the amino acids level. The N gene encoded a protein of 525 amino acids. Several sequence motifs were identified on the basis of conservation in the PPRVs and the morbilliviruses. The genome length of promoter region was 107 nucleotides with 91.8%-98.2% identity to other PPRV isolates. Phylogenetic analysis showed that the "China/Tib/Gej/07-30" belonged to the Asian lineage.


Assuntos
Animais , Feminino , Sequência de Aminoácidos , Sequência de Bases , China , Genoma Viral , Doenças das Cabras , Virologia , Cabras , Dados de Sequência Molecular , Proteínas do Nucleocapsídeo , Química , Genética , Peste dos Pequenos Ruminantes , Virologia , Vírus da Peste dos Pequenos Ruminantes , Química , Classificação , Genética , Filogenia , Regiões Promotoras Genéticas , Alinhamento de Sequência , Análise de Sequência
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