RESUMO
Teratomas are interesting because of their obscure origin,bizarre microscopic appearance and sometimes unpredictable behaviour.Although they occur infrequently in children, clinician should be aware of their clinical features, natural history, pathology and principles of treatment.In an attempt to document some of the features ,we report a case of an infant with large mediastinal teratoma presenting with severe and recurrent respiratory distress. Patient was operated successfully with no recurrence in 1 year follow up.
RESUMO
This prospective study was carried out to find the prevalence of developmental delay in 200 apparently healthy children below 2 years of age. Parents of the subjects were interviewed. The children were observed and assessed for their milestones on Trivandrum Developmental Screening chart (TDSC). The length, weight and head circumference of the children were measured and recorded. We could find out the prevalence of developmental delay in 9.5% of apparently healthy children by using a simple screening tool i. e. TDSC which can be administered in an office practice. If one can diagnose developmental delay in early stages of development, the early intervention can reduce a long term sequele.
Assuntos
Deficiências do Desenvolvimento , Serviços de Saúde da Criança , Educação InfantilRESUMO
Magic Bullet comprises of a specific synthesized drug in which metal ions play an important role. These drugs can be designed to treat and cure a specific disease by attacking on specifically diseased cells leaving aside the healthy ones, there by, increasing the efficiency of a drug. As metal ions are used since ages as immuno-modulators, they trigger the immunity, if combined with the durg. Thus, combination of drug can be chelated with metal ions, which can help to develop innovative strategies for preparing combinatorial drug, also known as “Magic Bullet” or metal complexes or mixed ligand complex in the light of the chelate hypothesis.