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Genet. mol. biol ; 27(4): 665-672, Dec. 2004. ilus, tab
Artigo em Inglês | LILACS | ID: lil-391245

RESUMO

The Human Genome Project has generated a large amount of sequence data. A number of works are currently concerned with analyzing these data. One of the analyses carried out is the identification of genes' structures on the junctions represent a type of signal present on eukariot genes. Many studies have appied Machine Learning techniques in the recognition of such regions. However, most of the genetic databases are characterized y the presence of noise data, which can affect the performance of the learning techniques. This paper evaluates the effectiveness of five data pre-processing algorithms in the elimination of noisy instances from two splice junction recognition datasets. After the pre-processing phase, two learning techniques, Decision Trees and Support Vector Machines, are employed in the recognition process.


Assuntos
Humanos , Biologia Computacional , Expressão Gênica , Biologia Molecular , Algoritmos , Inteligência Artificial , Dados de Sequência Molecular
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