RESUMO
Background: Renal colic is a common cause of acute severe pain. Opioids and non-opioids analgesics and NSAIDs and phosphodiesterase enzyme [PDE] inhibitors are four medical cathegories that recommended for treatment, but the relative efficacy of these drugs is uncertain
Materials and Methods: To examine the benefits and disadvantages of pethidine, piralgin, diclofenac and aminophyllin for the management of pain in acute renal colic, as a randomised clinical trial study, patients with four suspected renal colic[n=200] were randomised to receive these 4-drugs at emergency ward of -hospitals. Pain relief and side effects was assessed at one hour after the analgesics. Datas has been analised by statistical soft ware of SPSS-ver.11
Results: pain reliefed in the pethidine group after 30 minute and one hour was %60 [30 patients] and %94 [47 patients], for piralgin group was %54 [27 patients] and %92 [46 patients], diclofenac group was %28 [14 patients]and %68 [34 patients] and for aminophylline was %24 [12 patients] and %62 [31 patients]. [P< 0/05] The side-effects of 4-groups was included: pethidine: nausea [11 Patients], vomiting [7 Patients], respiratory depression [3 Patients] and headache [2 Patients]; piralgin [3 Patients]; aminophylline: orthostatic hypothension [7Patients], vertigue [9 Patients], headache [1 2 patients]; diclofenac had no side-effect
Conclusion: Tramadol response was as same as pethidine but less side-effects. diclofenac is a good choice for mild pain; but aminophyllin had a bad response with very much side-effects
RESUMO
Background: Renal colic is a common cause of acute severe pain. Opioids and non-opioids analgesics and NSAIDs and phosphodiesterase enzyme [PDE] inhibitors are four medical cathegories that recommended for treatment, but the relative efficacy of these drugs is uncertain
Materials and Methods: To examine the benefits and disadvantages of pethidine, piralgin, diclofenac and aminophyllin for the management of pain in acute renal colic, as a randomised clinical trial study, patients with four suspected renal colic [n=200] were randomised to receive these 4-drugs at emergency ward of -hospitals. Pain relief and side effects was assessed at one hour after the analgesics. Datas has been analised by statistical soft ware of SPSS-ver.11
Results: pain reliefed in the pethidine group after 30 minute and one hour was %60 [30 patients] and %94 [47 patients], for piralgin group was %54 [27 patients] and %92 [46 patients], diclofenac group was %28 [14 patients] and %68 [34 patients] and for aminophylline was %24 [12 patients] and %62 [31 patients]. [P< 0/05] The side-effects of 4-groups was included: pethidine: nausea [11 Patients], vomiting [7 Patients], respiratory depression [3 Patients] and headache [2 Patients]; piralgin [3 Patients]; aminophylline: orthostatic hypothension [7 Patients], vertigue [9 Patients], headache [12 patients]; diclofenac had no side-effect
Conclusion: Tramadol response was as same as pethidine but less side-effects. diclofenac is a good choice for mild pain; but aminophyllin had a bad response with very much side-effects