[Fibrodysplasia ossificans progressive: a case report]

Fibrodysplasia ossificans progressiva [FOP] is an extremely rare autosomal dominant disorder having variable expressivity with complete penetrance. FOP incidence has been estimated to be 1 per 2 million. FOP caused by mutations in ACVR1 gene encoding bone morphogenetic protein type-1 receptor. To date, 15 types of mutations have been reported. The majority of cases were determined to be the rsult of a new mutation occuring sporadically. Here we report a 20 years old girl who's suffering FOP for 11 years

[ effect Allium ampeloprasum feeding on serum level of glucose, triglyceride, and total cholesterol of diabetic rats]

Use of medicinal plants for attenuation of hyperglycemia and restoration of lipids to normal level is clinically important. Since garlic and leek are similar regarding some effective substances as well as the antidiabetic effect of garlic, this study was performed to evaluate the effect of chronic oral administration of leek [Allium ampeloprasum] on serum level of glucose, triglyceride, and total cholesterol of diabetic rats. In the current study, 36 male Wistar rats were randomly divided into 4 groups, i.e. control, AA-treated control, diabetic, and AA-treated diabetic group. The treatment groups received oral administration of plant-mixed pelleted food [6.25%] for 4 weeks. Serum glucose, triglyceride, and total cholesterol levels were measured in all animals prior to the treatmen as well as two and four weeks after the treatment. Serum glucose levels were increased 4 weeks after the treatment in diabetic group compared to those levels was observed one week before the treatment [P<0.0001] and also AA treatment of diabetic rats did exert a significant hypoglycemic effect as compared to untreated diabetics [p<0.05]. In addition, triglyceride levels were increased 4 weeks after the treatment in the diabetic group in comparison with related levels observed one week prior to the treatment [P<0.05] and there was a significant lower level of triglyceride in AA-treated diabetic rats [p<0.05]. Furthermore, a similar significant reduction was obtained for treated-diabetic group as compared to diabetic group regarding serum cholesterol level [p<0.01]. Oral chronic administration of AA could reduce serum glucose, triglyceride, and cholesterol levels of STZ-diabetic rats

[Determination of fauna and monthly activity of sandflies in the south of baft district, Kerman Province in 2004]

In the recent years, there has been an increasing rate of kala-azar disease in the south of Baft [Kerman/Iran]. A survey on the records of admitted patients in the main hospital of Kerman city from 1993- 2003 showed that from the total of 36 cases of visceral Leishmaniasis, 12 cases [33/3%] were from south Baft. Since awareness of visceral Leishmaniasis vectors status has a key role in disease control and programming, this study was carried out in order to determine the fauna, monthly activity, host preference, and susceptibility of dominant species to 4% D.D.T insecticide. For this purpose, 1710 sandflies [17 species] were collected by sticky traps and aspiratory methods and based on the standards during their monthly activity. The results of the investigation showed that the activity of sand flies starts in April and ends in October with two Peaks in July and September. The predominant species of this area were P. papatasi [33.74%] and P. alexandri [29.82%] that were observed during all months of sandflies activity. According to the result of blood-fed index by ELISA test and using dog and human antiserums, P. papatasi [43/3%] and P. alexandri [33/3%] were positive to human blood. Diagnostic dosage test showed that P. papatasi is susceptible to D.D.T 4% with one hour exposure