Prevalence of hepatitis C in lichen planus

Appraise the prevalence of hepatitis C in patients with lichen planus. This is a retrospective study concerning seventeen cases hospitalized for lichen planus between January 1992 December 2001. Hepatic check-up and anti HVC antibodies were searched in all patients. Cutaneous biopsy was systematic. Seventeen patients were hospitalized for lichen planus. The average age was 52.1 years [extreme between 12 years and 75 years]. Four had a positive hepatitis C serology so 23.5 percent of cases. Hepatic check-up was perturbed in three cases. Oral and erosive lesions were presents in here patients. The results of this retrospective study show a high prevalence of hepatitis C in lichen planus particularly with erosive oral lesions suggesting a relation ship between lichen planus and hepatitis C

dermatite atopique: aspects physiopathologiques et traitement

Atopic dermatitis represents the cutaneous facet of atopic disease. Its prevalence is in a regular increase these last decades. The physiopathology of this dermatitis is complex and not well known, implicating genetic, immunological, biochemical and environmental factors. The onset of Atopic dermatitis can start at any age of life. But it is exceptional before the age of two months; in the same way its onset after 20 years is relatively rare. It is an extremely polymorphous affection in its clinical expression that depends on the age of the subject, which necessitates establishment of diagnostic criteria. In spite of being benignity, atopic dermatitis is a chronic disease affecting negatively the quality of life of the majority of patients. The symptomatic treatment is based on topical corticosteroids and moisturizers. However, a better knowledge about its pathogenesis allows to hope for a therapeutic approach by immunomodulators, especially for the serious cases