RESUMO
It seems that internet involves increasing parts of people's daily lives, every day. In recent years, many reports have been published based on user's addiction to internet. The purpose of the present study was to evaluate predicting personality variables of internet addiction. Among internet users willing to cooperate in Ahvaz city net-shops and computer training centers, 100 people [56 female/44 male] were selected regardless of age, occupation and education. They completed Internet Addiction Questionnaire and NEO test. Population samples were divided into two groups: addicted and non-addicted. Their personality styles were determined based on two dimensions: Neuroticism and extroversion. Then data were analyzed using logistic regression model by SPSS software. According to this study 86% of users had internet addiction [56% mild, 28% moderate and 2% severe] and 14% did not. Twelve personality styles in terms of neuroticism and extroversion were entered in the logistic regression statistical models, internet addiction predictor styles included: stress vulnerability [p < 0.0001], and impulsively [p<0.05], Being active [p<0.05] and excitement policy [P < 0.05]. Also, there is a significant relationship between internet addiction, teen aging [P<0.03] and being unemployed [P < 0.0001]. According to the results of this study, it seems that personality styles are suitable predictors for vulnerability for internet addiction. The results suggest that internet users' character assessment, and identifying individuals at risk, can help prevent internet addiction
RESUMO
Neural stem cells exist in various regions of the developing and adult central nervous system [CNS]. They are undifferentiated cells, capable of both self-renewal and producing neurons and glial cells. In addition to generating different types of neural cells, NSCs are capable of producing cells of other tissues. In this study NSCs were isolated from mouse brain and their capability of differentiation into endothelial cells was evaluated. Neural stem cells [NSCs] were isolated from lateral wall of the lateral ventricle of the adult and fetal mouse brain and cultured in serum-free DMEM-F12 medium in the presence of basic fibroblast growth factor [bFGF], epidermal growth factor [EGF] and B27 supplement. Neurospheres were plated on the fibronectin coated culture slides. DMEM-F12 media supplemented with 10% FBS was used for differentiation of NSCs into endothelial cells. Differentiated cells were evaluated by Immuno-histochemistery, RT-PCR and tube formation assays. The results of this study revealed culture of fetal neural stem cells in fibronectin coated and also DMEM-F12 media containing 10% FRS led to differentiation of NSCs into endothelial cells. When differentiated cells were transferred into extra cellular matrix or matrigel, they produced capillary like structures characteristic of endothelial cells. The results of immuno-histo-chemistry and RT-PCR showed differentiated cells can absorb low density lipoproteins and express CD31, VE, cadherin and Flk-1 genes, and also can adhere to BS-1lectin. Unlike neural stem cells isolated from mouse fetus, the isolated cells from adult mouse brain did not differentiate into endothelial cells.This study reveals neural stem cells isolated from fetal mouse brain and adult mouse brain do not show similar behavior in differentiating into endothelial cells