propos d'une maladie de Hodgkin avec atteinte musculaire revelatrice

The localizations of the Hodgkin's disease in skeletal muscles are exceptional. On this matter, we report a personal observation in which the muscular attack is the revealing mode of the Hodgkin's disease. The mechanism of this muscular attack happens by contiguity starting from a lymph node. Finally, the problems of pronostic evaluation have been raised

Syndrome de Gougerot-Sjogren primitif avec gammapathie monoclonale A IGG et syndrome d'hyperviscosite sanguine

The authors have observed a primary Gougerot-Sj“gren's syndrome linked to a monoclonal gammapathy of IgG type kappa having been the origin of syndrome of blood hyperviscosity treated by the corticotherapy and the plasmatic exchanges. They reminded us of the elements that enable us to distinguish the primary Gougerot-Sj“gren's syndrome and discuss the prognosis value of the monoclonal gammapathy whose occurence is exceptional during the Gougerot-Sj“gren's syndrome

L'amyloidose du myelome multiple: a propos d'une observation personnelle avec revue de 52 cas de la litterature

We report one case of multiple myeloma complicated by diffuse amyloidosis and we make a re-view of 52 other cases in the literature. The frequency of this complication is 5-30% of multiple myelomas. The most frequent sites are: The digestive tract, the heart and vessels, the tongue, the kidney. the skin and the joints. Biochemically, this amyloidosis is classified as AL. Finally its occurence is a result of bad prognosis because its treatment is still disappointing

Approche diagnostique des fievres prolongees [a propos de 90 cas]

The etiological repartition of a series of 90 fevers of unknown origin observed in Moroccan adults has shown the following, percentages Infectious diseases 43,3% dominated by tuberculosis, 28,8% Haematological malignancies 27,7% dominated by Hodgkin's diseases 15.5% - Connective tissue diseases and rheumatic diseases 15.5% dominated by lupus erythematosus 8,9%- Cancers 10%- Miscellaneous 11% - Cases without a precisetiology 2,2%

Les complications infectieuses des hemopathies malignes [a propos de 69 observations

We have noticed 69 malignant hemopathies of complicates infections, The total of the infectious episodes is 94, that is 39,5% of frequency. Our malignant hemopathies are divided as follows: - Hodgkin's disease: 19 cases, that Is 27.6%. - Malignant lymphomas [without Hodgkin's disease]: 19 cases, that is 27%. - Acute leukemias: 11 cases, that is 19%. Chronic lmyeloid leukemia 10 cases. that is 14,5%. Multiple myeloma 6 cases, that is 8,6%. - Aplastic anemia 4 cases, that is 5,8%. The infectious episodes are divided as follows: Infections of the lungs without tuberculosis 16 cases, that Is 23,2%. - Infections of the skin, lymph node and light ports.16 cases, that is 23,2%. - Tuberculosis: 10 cases, that is 14.5%. Urinary tract infections 10 cases, that is 14,5%. - Purulent meningitis: 2 cases, that is 2,9%. - Zoster: 2 cases, that is 2.9%. On that other hand, is 20 cases of 69, that is 21% we have found 2 or 3 infectious episodes 80% of which have occurred during malignant lymphomas. Finally, we have recorded 10 deaths and a good evolution of the infections is the other cases

Apport diagnostique de la biopsie des ganglions peripheriques dans un service de medecine interne [a propos de 280 prelevements]

The retrospective study of peripheral lymph node biopsies over a period of 13 years [1972 - 1984] has revealed a total of 286 biopsies taken of 253 patients. This study has led to the following conclusions * The diagnostic contribution of this biopsy in not to be demonstrated any more. The profitability in our series which is of 88,9% shows that. * The etiological repartition is dominated by the following percentages * Tuberculosis 44%, *Hodgkins disease 13.4%. * Non hodgkin's lymphomas 13%.* The maximal of benign in volument and haematological malignances is observed before 30 years and the maximal of neoplasm meta stasis is observed after 30 years

Place de la corticotherapie en pathologie infectieuse

Nowadays, the corticotherapy presents better defined indications in the infectious diseases. These indications from physiopathologic notions and must be thought of taking into consideration the pro-infectious effect of these drugs. There is no infectious disease that was systematically treated by corticosteroids. The corticotherapy is used either for a curative purpose or a prophylactic one The infectious diseases. Susceptible to be treated by the corticosteroids in certain forms are basically * Bacterial infections Tuberculosis, typhoid fever, purulent meningitis, brucellosis, cough, syphilis, diphtheria and leprosy. * Viral infections Mononucleosis infectious, zoster, variceila and mumps

Effects des corticosteroides sur l'immunite anti-infectieuse

The infectious complications are sometimes one of the ransons to be paid during the corticotherapy because of the immunodepression induced by the corticosteroids over the different stages of anti-infectious immunity. These many things are altered: the phagocytosis and bactericidis, the immunity of cellular mediation, the antibody and interferon production. On the contrary, the corticotherapy has no effect on the complement. This inequal attack of immunity defences against the infection explains the type of infection noticed during the corticotherapy

Revue generale des abces de la rate

The non-specific bacterial abscesses of the spleen are scarce. Their diagnosis is difficult and requires scintigraphy and echography of the spleen. From a pathogenic point of view, we distinguish the hematogenic abscess, the abscess of an exterior origin and those of an interior one. Staphylococcus, streptococcus and the negative -Gram bacilli are considered to be the most frequent in this pathology. The spontaneous evolution is enameled by numerous complications. The treatment is based on splenectomy and antibiotherapy before the operation and after