RESUMO
Introduction: The lack of agreement between job demands and worker capacity and repetitive / restless working may lead to cumulative trauma disorders. These disorders occur during months and years of facing with extra-physical and psychological stressor in work environment. This study was conducted among workers of an aluminum industry in Hormozgan to determine the prevalence of CTDs and MSDs. The result of this study can be used to develop CTD preventive strategies in the workplace towards improving workers health
Methods: In this descriptive cross-sectional study 200 workers from 6 production units of the factory were studied by Nordic musculoskeletal questionnaires [NMQ] and the prevalence of CTDs and MSDs was measured. Data analysis was performed by Spss 15 software and chisquare test
Results: The highest percentage of neck and waist CTDs was found in crane drivers and the highest percentage of wrist/hand and shoulders CTDs respectively were found in welding and Anode production workers. A Significant relationship was found between the CTDs at waist and height and age, weight and work history at 0.05 significance level. In addition, work history and age showed a significant relationship with wrist/hand CTDs
Conclusion: The high prevalence of CTDs in this study with regarding to this point that majority of the studied workers had a short work history indicated that attention to this problem is necessary. Therefore application of control measures to eliminate or reduce exposure of employee to the ergonomics stressors associated with the development of CTD is recommended
RESUMO
Gold nanoparticles are one of the most applicable metal nanoparticles which are widely being used in different fields such as nanomedicine and nanobiotechnology. The goal of this study is the production of gold nanoparticles with appropriate size by the use of Glutamic acid which is considered as a green method. For diagnostic application the synthesized gold nanoparticles would be than conjugated with anti-morphine antibody. In this experimental study, gold nanoparticles were synthesized and coated by chemical reduction method with the use of Glutamic acid. Formation of gold nanoparticles and their size were recognized and measured by UV-Vis spectroscopy, Dynamic light scattering and Transmission electron microscopy. Anti-morphine antibody was purified and prepared by subcutaneous injection of 400 micro g/ml dose of morphine vaccine to 9 rabbits. Study of immunity, immunogenicity and antibody production was performed by immuno-diffussion methods. After production and recognition of colloidal gold nanoparticles they were changed into suspension by the use of PBS buffer. They were then conjugated with anti-morphine antibody and incubated at 4 degree C for 115 hours. Conjugated nanoparticles were characterization by SDS-PAGE and UV-V is spectroscopy. The highest absorption of these particles was at 525 nm and their size was about 20 nm formed bands pertaining to conjugated nanoparticles were displaced in compare with standard samples. Glutamic acid is capable of synthesizing gold nanoparticles and since amino acids are intoxic, the nanoparticles which are synthesized by the use of amino acids, would be applicable in medicine and biotechnology. Nanoparticles conjugated with antibodies, could be also used as recognition tools.