[Granulosa cell tumor associated with chondrosarcoma of iliac: a case report]

The association of an ovarian tumor with Ollier's disease [multiple encondromatosis] is a known entity but chondrosarcoma and ovarian tumors is rare. Only one case with Ollier's disease was reported. In this clinical presentation we report a patient with granulosa cell tumor and chondrosarcoma Our patient was a 20 year old woman with acute abdominal symptoms and adnexal mass. She had emergency surgery. Ovarian mass was removed and sent for pathologic study. Ovarian granulosa cell tumor was reported. In the next follow-up CTscan reported osteolitic mass of iliac bone. Biopsy was done and was compatible with chondrosarcoma of iliac. Then radical surgery and resection of iliac bon was performed. Due to the demand for fertility preservation, she was undergoing chemotherapy. There is a risk of malignant change to chondrosarcoma or other bone tumours in Ollier's Disease. The attractive point of this patient is the association of ovarian tumor with primary iliac chondrosarcoma that has not been reported .Concurrent findings may help future research in finding the cause, early diagnosis and appropriate treatment of tumor

Report of a rare case of unprescribed long-term use of dexamethasone injection for 20 years

Background and Purpose: Most corticosteroids are dose- and duration-dependent. Dexamethasoe has been the highly used drug in the country in the last years, and can produce a pseudokushing syndrome if use in the long run. In the present paper, we will report a case of dexamethasone use for twenty years

The Patient: The patient is 52-year old man, married but has no child; he has started injecting dexamethasone 30 years ago; he keeps cattle and has a farm too. The patient was hospitalized first with a diagnosis of drug-resisitant brucellosis in Jovein, Iran. Laboratory tests indiated anemia, leukocytosis, hypocalemia, hypocalcemia and hyponathremia; he was discharged from the hospital four days later. Two days later, he was referred to neurocerebral surgeon due to backache, lower and upper limbs numbness, and walking disorder with a diagnosis of spastic quadriparesia and babinsky. Sixteen days after that, he underwent a total laminectomy surgery of C3-C6 with the diagnosis of cervical myelopathy. He had already been hospitalized in Mashad, Iran for a fever of unknown causes two years before that, and cataract surgery of both eyes

Conclusion: Long-term use of dexamthasone has caused six hospitalizations, diagnostic measures, medical interventions and surgical procedures for the patient reported here