Hair Dye [Paraphenylene diamine]: systemic and kidney toxicity

Paraphenylene diamine [PPD] is a compound used in hair dye formulations. Intoxication with PPD [intentionally or accidentally] can lead to potentially fatal systemic complications. Angioneurotic oedema and acute renal failure are common complications of PPD intoxication. Other systems are also involved including respiratory and cardiovascular systems. Hepatic, neurological, muscular and ophthalmic toxicities are also common manifestations. Careful history and clinical examination is essential order to reach a diagnosis and to initiate timely therapy