Association between anthropometric measures and bone mineral density: population-based study

Osteoporosis is a major public health concern around the world. It has been shown that bone mineral density is correlated to anthropometric measures like height and weight, but this association may vary depending on ethnic and environmental factors. The aim of this study was to identify probable relations between anthropometric measures and bone mineral density. In this population-based study, we compiled the data collected from Iranian Multicenter Osteoporosis Study to assess the possible associations between different anthropometric indices and bone mineral density at femur and lumbar spine. The gathered data was analyzed using t-test and one way ANOVA. Data was available for 4445 subjects, consisting 1900 males [42.7%] and 2545 females [57.3%]. We observed statistically significant correlations between bone mineral density and height, weight, waist circumference, hip circumference, waist to hip ratio and body mass index [BMI]. Based on the result of linear regression modeling studies, BMI could be considered an independent predictor of bone mineral density. Iranian population shows similar measures compared to analogous studies in other populations. Lower weight should be carefully considered as a predisposing factor for bone loss and osteoporosis

Comparing acute clinical intrahemodialysis complications and biocompatibility of polysulfone versus hemophane membranes

The membranes used in haemodialysis may be manufactured from cellulose, modified cellulose or synthetic polymers. Such membranes, when in contact with blood will activate the complement system, which entails changes in leukocyte and platelet counts. Polysulfone is a synthetic membrane of high biocompatibility standards, whereas haemophane membranes are modified cellulose-based membranes. The biocompatible profiles of these membranes, has been studied by clinical reactions [i.e. hypotension, nausea, pruritis, ...] during dialysis sessions. Both kinds of these membranes are used in Iran. The number and severity of these reactions define the degree of dialysis biocompatibility. In a clinical trial study which was carried out in Imam Khomeini hospital hi Tehran, 100 hemodialysis patients were enrolled to this investigation. Their clinical reactions were compared during 3 sessions of hemodialysis with polysulfone and 3 sessions of hemodialysis with hemophan membrane. Each patient was the control of him/herself. Data was analyzed using Chi square test. Mean age of patients was 48.85 +/- 17.56 years and 39% of them were female. The most common complications were hypotension and muscle cramps [each 21.5%]. Hypotension was higher in sessions of polysulfon versus hemophane [18% versus 25%] but was not significantly different. Also other complications such as muscle cramp, nausea, vomiting, dyspnea, headache, chills and fever had no signific n difference. Seizure did not occur in any patient. According to our findings the membrane's type has no role in acute clinical complications during hemodialysis and in most patients, membranes can be used according to their availability. It seems their biocompatibility has no considerable clinical difference