Clustering of cardiovascular risk factors in diabetics and IGT cases in Isfahan province 2000-2001: Isfahan healthy heart program

This study was conducted to cluster cardiac risk factors of patients and to compare the prevalence of these risk factors in diabetic patients and patients with glucose intolerance with normal people, and also to compare the prevalence of these factors in known and new cases of diabetes mellitus. This descriptive cross-sectional study was conducted on a sample selected from Isfahan province, Iran, as part of a national program for cardiovascular diseases prevention and control. A total of 3940 male and female subjects [1914 males, 2026 females] aged above 19 years were studied. The demographic characteristics were obtained by questionnaire. Important risk factors such as Systolic Blood Pressure [SBP], Diastolic Blood Pressure [DBP], Waist Circumference [WC], Body Mass Index [BMI], Fasting Blood Sugar [FBS], Triglyceride [TG], Total Cholesterol [TC], High Density Lipoprotein [HDL-C], and Low Density Lipoprotein [LDL-C] were assessed in the subjects. The prevalence of known cases of diabetes, new cases of diabetes, and glucose resistance was 4.3%, 1.1%, and 6.2% in the population under study, respectively. The prevalence of the above conditions was 4.9%, 1.2% and 1.1% in women, and 3.7%, 1% and 5.3% in men, respectively. Comparison of the prevalence of blood lipid disorders showed a significant difference between patients and healthy individuals. The overall comparison of all of the risk factors also showed a significant difference between the said groups. The prevalence of blood lipid disorders in men was higher than in women and this difference was significant. Comparison of the prevalence of increased BMI/WC and blood lipid disorders between two sexes revealed a significantly higher prevalence in women. The results of this study indicate a high prevalence of risk factors, especially increased prevalence of obesity and blood lipid disorders in cases of diabetes and glucose intolerance. Hence, strategies for prevention and treatment of diabetes should be launched in the community in view of the extent of these risk factors

Clustering of cardiovascular risk factors in diabetic and glucose intolerant cases

Comparing to other people, diabetic patients have a greater chance to develop cardiovascular diseases. To compare the prevalence of cardiac risk factors in diabetic patients, glucose intolerant patients and the normal individuals. Also, a comparison on prevalence of these factors in known and new cases of diabetes mellitus was made. This cross-sectional study was done on 3940 samples [1914 males, 2026 females] in the age group of >/= 19 years old. The samples were chosen base on random-clustering method. The demographic characteristic information was obtained using questionnaires. The major risk factors such as systolic/diastolic blood pressure, waist circumference, body mass index, fasting blood sugar, serum lipids were obtained through laboratory studies, physical examinations and observations. The data were statistically analyzed using SPSS software. The prevalence of known diabetes, new cases of diabetes, and glucose intolerance among the total cases were 4.3%, 1.1%, and 6.2%, respectively. The prevalence of the similar parameters in female and male groups was 4.9%, 1.2%, 1.1% and 3.7%, 1%, 5.3%, respectively. Comparing only the abundance of blood lipids disorders among patients and healthy individuals was indicating of the presence of a significant difference, statistically. The same statistical pattern was obtained when all risk factors among patient and healthy groups were compared, collectively. The prevalence of blood lipids disorders in men was higher than those in women showing a significant difference. When the prevalence of risk factors including an increase in BMI or WC compared with blood lipids disorders between two sexes, the prevalence rate was significantly higher in women than in men [P<0.05]. Based on data obtained in this study, the preventive and therapeutic for diabetic patients should be launched according to the extent of these risk factors