RESUMO
Controlling risk factors such as dyslipidemia in patients with coronary artery disease, including candidates for coronary artery bypass grafting [CABG], is of great importance and has serious effects on CABG morbidity and mortality. The aim of this study was to evaluate lipid serum levels, comprising TG, LDL, and HDL, before CABG and their relation with in-hospital outcome. The clinical profiles of 3,593 patients in the hospital cardiac surgery databank who underwent isolated CABG between April 2006 and April 2008 were reviewed. Three components of lipid profile, including TG, LDL, and HDL serum levels, were checked all the time of hospitalization in all the patients. Lipid control was evaluated according to the published guidelines. The mean LDL, HDL, and TG serum levels were 103.4 +/- 48.5, 40.9 +/- 16, and 168 +/- 87 mg/dl, respectively. Additionally, 487 [13.6%] patients had entire TG, LDL, and HDL serum levels within the acceptable range and in 668 [18.6%] patients, all of these components were within the uncontrolled range. After adjustment for confounders, in-hospital mortality in patients with uncontrolled TG, LDL, and HDl was higher than patients with controlled TG, LDL, and HDl [p value=0.042, OR=1.299, 95% CI =1.012-1.934]. The high prevalence of uncontrolled lipids in our patient population is alarming. Regular and frequent pre- and post-operative visits to monitor and modify patient risk factors, including dyslipidemia, seem necessary. An increase in stain dosage or adjunctive therapy with other lipid lowering agents may be helpful. Attempts to maintain all lipids the controlled range may have beneficial effects on hospital outcome
RESUMO
Pre-eclampsia is a systemic disorder which is associated with hypertension and proteinuria and may develop from 20 weeks of gestation. Pre-eclampsia affects different organs of the body. The present study is an attempt to check the effect of pre-eclampsia on retina using electroretinography. A total of 82 pregnant subjects divided in 2 groups [41 normal pregnant subjects as control and 41 pre-eclampsia pregnant patients as case group]. The total population was undergone electroretinographic examination in Qods center. ERG is a technique to examine the retina. Latency and amplitude of b wave of ERG were recorded and compared in 2 groups. The results showed no statistically significant difference between the age of the two groups [p>0.05 for 24.56 +/- 3.5 in control and 25.33 +/- 3.9 in case group]. Mean latency and standard deviation of ERG b wave in control and case groups were 128.77 +/- 24.85 and 125.10 +/- 22.56 msec, respectively. Mean amplitude and standard deviation of ERG wave in control and case groups were 43.27 +/- 2.3 and 43.44 +/- 2.7 micro r, respectively. Therefore no significant difference [p >0.05] was obtained in two groups. It was concluded that pre-eclampsia had no adverse effect on retina and more research is needed to perform to reach a certain conclusion