Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 4 de 4
Filtrar
Adicionar filtros








Intervalo de ano
1.
Journal of Gorgan University of Medical Sciences. 2017; 19 (2): 84-90
em Persa | IMEMR | ID: emr-189303

RESUMO

Background and Objective: Enterococci is gram positive bacteria which is the inhabitants of gastrointestinal tract. Hospital infections and antibiotic resistance to enterococci is increased. This study was done to determine the molecular evaluation of vanA and vanB genes of enterococci isolates resistant to Vancomycin and Teicoplanin


Methods: In this descriptive study, 113 isolates samples were collected and identified according to biochemical test and cultural characteristics in Ali ibn Abi Talib hospital in Zahedan, Iran. Antibiogram test was done to determine antibiotic resistance pattern. E-test strip was used to evaluate the minimum inhibitory of concentration [MIC]. PCR was used to detect the vanA and vanB genotype in Vancomycin and Teicoplanin resistance enterococci


Results: 92%, 6.2% and 1.8% of isolated samles collocted from urine, blood culture and pleura fluid, respectively. According to phenotype, 18.6% and 17.69% were resistance to Vancomycin and Teicoplanin, respectively. Resistance was observed in strains of Enterococcus faecalis and Enterococcus faecium. VanA genotype was seen in all of the resistance isolated species


Conclusion: This study showed that strains of Enterococcus faecalis and Enterococcus faecium have more antibiotic resistance to the Vancomycin and Teicoplanin, morever vanA genotype precence in all of resistance isolated samples


Assuntos
Enterococcus/genética , Teicoplanina , Proteínas de Bactérias , Carbono-Oxigênio Ligases , Genótipo , Resistência Microbiana a Medicamentos , Vancomicina
2.
Journal of Sabzevar University of Medical Sciences. 2011; 18 (1): 26-32
em Persa | IMEMR | ID: emr-180016

RESUMO

Background and Purpose: Patients whit body dysmorphic disorders have dysfunctional negative thoughts about their physical appearance. The purpose of this study was to evaluate the effectiveness of metacognitive intervention on body dysmorphic disorder in a 20-year-old male case


Methods and Materials: This case study used the single case experimental design to reduce the symptoms of a male patient with BDD diagnosis. To collect the data, the client completed the questionnaire in pre-test [as a base-line], last treatment session [as the post-test], and six months after treatment [follow-up]: Yale-Brown Obsessive Compulsive Scale Modified for BDD [YBOCS-BDD], Thought Fusion Instrument [TFI], Body Dysmorphic Metacognition Questionnaire [BDMCQ], and Beck Anxiety inventory [BAI]. For data analysis, the data chart analysis and graphical methods were used and based on the ascending and descending trend of the scores, effectiveness of the intervention was judged


Results: The scores for the pre-test, post-test, and follow-up examinations were 30, 10, and 10, respectively. His scores of the TFI were 820, 100, and 120, respectively. Finally, the scores for BDMCQ came up to be 45, 10, and 11, respectively, and the scores for [BAI] were: 47-16-18 respectively. Based on the clinical significance measures, the reduction of the symptoms was significant


Conclusion: The metacognitive intervention is effective in reducing the symptoms of the body dysmorphic disorder

3.
Iranian Cardiovascular Research Journal. 2009; 3 (1): 1-7
em Inglês | IMEMR | ID: emr-119032

RESUMO

LVNC is a genetic cardiac disease of emerging importance with a distinct clinical and pathophysiological presentation. The diagnosis of LVNC, however, is often missed, most often as a consequence of ignorance of the condition. Echocardiography is considered the reference standard for the diagnosis of LVNC. Prognosis remains poor for patients with impaired systolic left ventricular function, as treatment options are very limited. Because of the familial association of LVNC, first-degree relatives should be screened by Echocardiography


Assuntos
Humanos , Cardiomiopatias/genética , Cardiopatias/congênito , Ecocardiografia , Prognóstico , Disfunção Ventricular Esquerda , Família , Cardiomiopatias/classificação , Eletrocardiografia , Arritmias Cardíacas
4.
Journal of Sabzevar University of Medical Sciences. 2006; 13 (2): 74-79
em Persa | IMEMR | ID: emr-179914

RESUMO

Background and Purpose: P53 gene is a tumor suppressive gene and its product, P53 protein, is a protective factor against tumor formation that inhibits the extension of genetically damaged cells. P53 aggregation in tumoral cell nucleus is related with p53 gene mutations, which can be detected by immunohistochemical methods. This study was designed to investigate the protein aggregation in patients with gastric cancer in Gorgan, Iran


Methods and materials: All paraffin-embedded blocks of gastric cancer cases during the years 2000 to 2004 in the pathology ward of the 5th Azar Hospital in Gorgan, Iran [111 cases altogether] were evaluated and stained, for detecting microtome cutting. The obtained data were entered into SPSS and chisquare was used for analysis


Results: 111 cases with gastric cancer were investigated. The most frequent type of gastric tumor was adenocarcinoma [66.7%]. In 59.5% of the affected cases, P53 protein was detected. No significant relationship was observed between P53 expression and factors such as age, gender, and histological type of the tumor


Conclusions: In this study, P53 protein rate was high but it showed no significant relationship with other variables. We suggest further studies to discover the relationship between protein aggregation in tumor cells and other variables in affected cases

SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA